DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6813 and ZNF736

DIOPT Version :9

Sequence 1:NP_001163590.1 Gene:CG6813 / 41396 FlyBaseID:FBgn0037923 Length:294 Species:Drosophila melanogaster
Sequence 2:NP_001164376.1 Gene:ZNF736 / 728927 HGNCID:32467 Length:427 Species:Homo sapiens


Alignment Length:317 Identity:82/317 - (25%)
Similarity:119/317 - (37%) Gaps:65/317 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 RICSRSDAPIDLFGPGNGHLVRQIHSITGVELSCKKEISGQ---------------MCTTCLDNL 56
            ::..|.....||   .|.||.:...|:.    :||.:.|..               .|..|....
Human    97 KVILRKYGSCDL---NNLHLKKDYQSVG----NCKGQKSSYNGLHQCLSATHSKTCQCNKCGRGF 154

  Fly    57 QAAIKFRQRCIIAEKQNLERIECDSKDCSTDPIIYEDIDDNQIESELDESILCPEVKDLPMPSAE 121
            |....|.:...|..::...:.|...|||.    ::.|...::....::....|.|..    .:.:
Human   155 QLCSIFTEHKDIFSREKCHKCEECGKDCR----LFSDFTRHKKIHTVERCYKCEECG----KAFK 211

  Fly   122 KVSAPTSLNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKE 186
            |.|   :|...|.:..|..||.|..||:.....|...:|...|||.:.:.|.  .|.::|....:
Human   212 KFS---NLTEHKRVHTGEKPYKCEGCGKTFTCSSTLVKHKRNHTGDRPYKCE--ECGKAFKCFSD 271

  Fly   187 LTSHTRIHTGEQPYVC-----VY-----------------------CPRRFSSSGARQEHHRRHR 223
            ||:|.||||||:||.|     .|                       |.:.|....|..:|.|.|.
Human   272 LTNHKRIHTGEKPYKCEECNKAYRWFSDLAKHKIIHTGDKPYTCNECGKAFKWFSALSKHKRIHT 336

  Fly   224 NERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSSNIH 280
            .|:.|.|:.|.|:|..|..|..||.||::.|.:.|..|.|.||..|.|..|  ..||
Human   337 GEKPYICEECGKAFTRSSTLFNHKRIHMEERPYKCEECSKTFKCFSDLTNH--KRIH 391

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6813NP_001163590.1 zf-AD 6..76 CDD:285071 15/83 (18%)
C2H2 Zn finger 144..164 CDD:275368 5/19 (26%)
C2H2 Zn finger 172..194 CDD:275368 7/21 (33%)
zf-H2C2_2 186..211 CDD:290200 15/52 (29%)
UFD2 <256..>294 CDD:227443 10/25 (40%)
C2H2 Zn finger 258..280 CDD:275368 8/21 (38%)
ZNF736NP_001164376.1 KRAB 4..63 CDD:214630
KRAB 4..43 CDD:279668
C2H2 Zn finger 147..167 CDD:275368 4/19 (21%)
C2H2 Zn finger 175..195 CDD:275368 5/23 (22%)
C2H2 Zn finger 203..223 CDD:275368 6/26 (23%)
zf-H2C2_2 215..240 CDD:290200 8/24 (33%)
COG5048 <227..383 CDD:227381 50/157 (32%)
C2H2 Zn finger 231..251 CDD:275368 5/19 (26%)
zf-H2C2_2 244..268 CDD:290200 7/25 (28%)
C2H2 Zn finger 259..279 CDD:275368 7/21 (33%)
zf-H2C2_2 271..294 CDD:290200 12/22 (55%)
C2H2 Zn finger 287..307 CDD:275368 2/19 (11%)
C2H2 Zn finger 315..335 CDD:275368 5/19 (26%)
zf-H2C2_2 327..352 CDD:290200 10/24 (42%)
C2H2 Zn finger 343..363 CDD:275368 8/19 (42%)
C2H2 Zn finger 371..391 CDD:275368 8/21 (38%)
zf-H2C2_2 383..407 CDD:290200 4/11 (36%)
C2H2 Zn finger 399..419 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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