DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6813 and ZSCAN31

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001128687.1	Gene:	ZSCAN31 / 64288	HGNCID:	14097	Length:	406	Species:	Homo sapiens

Alignment Length:	256	Identity:	76/256 - (29%)
Similarity:	111/256 - (43%)	Gaps:	53/256 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 ELSCKKEISGQMCTTCLDNLQAAI----KFRQRC---IIAEKQNL-----ERIECDSKDCSTDPI 89
            ||:.|:||..:|.......||..:    |:|:.|   ..||||..     .|..|:  :|.
Human   187 ELASKQEILKEMEHLGDSKLQRDVSLDSKYRETCKRDSKAEKQQAHSTGERRHRCN--ECG---- 245

  Fly    90 IYEDIDDNQIESELDESILCPEVKDLPMPSAEKVSAPTSLNHQKSIGGGTGPYVCPDCGRIINNK 154
                      :|....|:|                    :.||: |..|..||.|.:||:..:.:
Human   246 ----------KSFTKSSVL--------------------IEHQR-IHTGEKPYECEECGKAFSRR 279

  Fly   155 SNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRIHTGEQPYVCVYCPRRFSSSGARQEHH 219
            |:..||...|||.|.:.|  ..|.::|:....||.|.||||||:||.|..|.:.|..|....:|.
Human   280 SSLNEHRRSHTGEKPYQC--KECGKAFSASNGLTRHRRIHTGEKPYECKVCGKAFLLSSCLVQHQ 342

  Fly   220 RRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSSNIH 280
            |.|..|:||:|..|.|:|:.:..|.:|..:|...:.:.|..|.|.|.:.:.|..|  ..||
Human   343 RIHTGEKRYQCRECGKAFIQNAGLFQHLRVHTGEKPYQCSQCSKLFSKRTLLKKH--QKIH 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	15/50 (30%)
		C2H2 Zn finger	144..164	CDD:275368	6/19 (32%)
		C2H2 Zn finger	172..194	CDD:275368	7/21 (33%)
		zf-H2C2_2	186..211	CDD:290200	14/24 (58%)
		UFD2	<256..>294	CDD:227443	8/25 (32%)
		C2H2 Zn finger	258..280	CDD:275368	6/21 (29%)
ZSCAN31	NP_001128687.1	SCAN	35..146	CDD:128708
		SCAN	35..123	CDD:280241
		COG5048	<156..397	CDD:227381	73/248 (29%)
		zf-C2H2	239..261	CDD:278523	7/58 (12%)
		C2H2 Zn finger	241..261	CDD:275368	7/56 (13%)
		zf-H2C2_2	254..278	CDD:290200	10/44 (23%)
		C2H2 Zn finger	269..289	CDD:275368	6/19 (32%)
		zf-H2C2_2	281..305	CDD:290200	8/25 (32%)
		C2H2 Zn finger	297..317	CDD:275368	7/21 (33%)
		zf-H2C2_2	310..332	CDD:290200	13/21 (62%)
		C2H2 Zn finger	325..345	CDD:275368	6/19 (32%)
		zf-H2C2_2	338..362	CDD:290200	10/23 (43%)
		C2H2 Zn finger	353..373	CDD:275368	6/19 (32%)
		zf-H2C2_2	366..389	CDD:290200	6/22 (27%)
		C2H2 Zn finger	381..401	CDD:275368	6/21 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050