DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6813 and ZKSCAN7

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001275519.1	Gene:	ZKSCAN7 / 55888	HGNCID:	12955	Length:	754	Species:	Homo sapiens

Alignment Length:	153	Identity:	55/153 - (35%)
Similarity:	79/153 - (51%)	Gaps:	4/153 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 SLNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTR 192
            ||...:.:..|..||.|.:|||...:..|..:|...|||.|.:.|  ..|.::|:..|.|..|..
Human   509 SLARHQVLHTGKKPYKCNECGRAFCSNRNLIDHQRIHTGEKPYEC--SECGKAFSRSKCLIRHQS 571

  Fly   193 IHTGEQPYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHY 257
            :||||:||.|..|.:.|:.:....||.|.|..|:.:||..|.|:|..|.||.:|:.:|...:.:.
Human   572 LHTGEKPYKCSECGKAFNQNSQLIEHERIHTGEKPFECSECGKAFGLSKCLIRHQRLHTGEKPYK 636

  Fly   258 CYVCQKHFKRISHLMTHLSSNIH 280
            |..|.|.|.:.|||:.|  ..||
Human   637 CNECGKSFNQNSHLIIH--QRIH 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071
		C2H2 Zn finger	144..164	CDD:275368	6/19 (32%)
		C2H2 Zn finger	172..194	CDD:275368	6/21 (29%)
		zf-H2C2_2	186..211	CDD:290200	11/24 (46%)
		UFD2	<256..>294	CDD:227443	10/25 (40%)
		C2H2 Zn finger	258..280	CDD:275368	8/21 (38%)
ZKSCAN7	NP_001275519.1	SCAN	51..161	CDD:128708
		SCAN	51..138	CDD:280241
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	157..215
		KRAB_A-box	231..270	CDD:143639
		COG5048	380..738	CDD:227381	55/153 (36%)
		zf-C2H2	383..405	CDD:278523
		C2H2 Zn finger	385..405	CDD:275368
		zf-H2C2_2	401..422	CDD:290200
		C2H2 Zn finger	413..433	CDD:275368
		zf-H2C2_2	426..450	CDD:290200
		C2H2 Zn finger	441..461	CDD:275368
		zf-H2C2_2	453..478	CDD:290200
		C2H2 Zn finger	469..489	CDD:275368
		zf-H2C2_2	482..506	CDD:290200
		C2H2 Zn finger	497..517	CDD:275368	2/7 (29%)
		zf-H2C2_2	509..532	CDD:290200	9/22 (41%)
		C2H2 Zn finger	525..545	CDD:275368	6/19 (32%)
		zf-H2C2_2	537..562	CDD:290200	9/26 (35%)
		C2H2 Zn finger	553..573	CDD:275368	6/21 (29%)
		zf-H2C2_2	566..590	CDD:290200	11/23 (48%)
		C2H2 Zn finger	581..601	CDD:275368	6/19 (32%)
		zf-H2C2_2	594..616	CDD:290200	9/21 (43%)
		C2H2 Zn finger	609..629	CDD:275368	8/19 (42%)
		zf-H2C2_2	622..646	CDD:290200	7/23 (30%)
		C2H2 Zn finger	637..657	CDD:275368	8/21 (38%)
		zf-H2C2_2	649..674	CDD:290200	5/11 (45%)
		C2H2 Zn finger	665..685	CDD:275368
		zf-H2C2_2	677..701	CDD:290200
		C2H2 Zn finger	693..713	CDD:275368
		zf-H2C2_2	706..730	CDD:290200
		C2H2 Zn finger	721..741	CDD:275368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	735..754
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960