DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6813 and ZNF444

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_060807.2	Gene:	ZNF444 / 55311	HGNCID:	16052	Length:	327	Species:	Homo sapiens

Alignment Length:	184	Identity:	47/184 - (25%)
Similarity:	69/184 - (37%)	Gaps:	55/184 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 PSAEKVSAPTSLNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFA 182
            |..::.|:|.......:.....|...||:||:               |.:|..|
Human   155 PYKQEPSSPPLAPGLPAFLAAPGTTSCPECGK---------------TSLKPAH----------- 193

  Fly   183 TRKELTSHTRIHTGEQPYVCVYCPRRFSSSGARQEHHRRHRN-------------------ERRY 228
                |..|.:.|:||:|:.|..|.:.|    .|:||.||||:                   |:.:
Human   194 ----LLRHRQSHSGEKPHACPECGKAF----RRKEHLRRHRDTHPGSPGSPGPALRPLPAREKPH 250

  Fly   229 ECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSSNIHKR 282
            .|..|.|:|.....|.:|:..|..||...|:.|.|.|.|..|::.|  ..||.|
Human   251 ACCECGKTFYWREHLVRHRKTHSGARPFACWECGKGFGRREHVLRH--QRIHGR 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071
		C2H2 Zn finger	144..164	CDD:275368	4/19 (21%)
		C2H2 Zn finger	172..194	CDD:275368	2/21 (10%)
		zf-H2C2_2	186..211	CDD:290200	9/24 (38%)
		UFD2	<256..>294	CDD:227443	10/27 (37%)
		C2H2 Zn finger	258..280	CDD:275368	7/21 (33%)
ZNF444	NP_060807.2	SCAN	21..98	CDD:366881
		PRK14959	<60..>182	CDD:184923	4/26 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	101..171		3/15 (20%)
		COG5048	<179..>280	CDD:227381	33/134 (25%)
		C2H2 Zn finger	181..201	CDD:275368	9/49 (18%)
		C2H2 Zn finger	209..229	CDD:275368	10/23 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	220..243		6/22 (27%)
		C2H2 Zn finger	252..272	CDD:275368	6/19 (32%)
		zf-C2H2	278..300	CDD:333835	7/23 (30%)
		C2H2 Zn finger	280..300	CDD:275368	7/21 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050