DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6813 and ZNF562

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001123503.1	Gene:	ZNF562 / 54811	HGNCID:	25950	Length:	426	Species:	Homo sapiens

Alignment Length:	145	Identity:	52/145 - (35%)
Similarity:	70/145 - (48%)	Gaps:	2/145 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 GTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRIHTGEQPYVC 202
            |...:.|.:|||...|.|:|..|...|||||...|.  .|.::|.....||.|.|.|||.:||.|
Human   284 GEKSFECKECGRSFRNSSSFNVHIQIHTGIKPHKCT--ECGKAFTRSTHLTQHVRTHTGIKPYEC 346

  Fly   203 VYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKR 267
            ..|.:.|:.......|.|.|..|:.|:|..|.|:|..|..|.:|:.||...:.:.|..|.|.|..
Human   347 KECGQAFTQYTGLAIHIRNHTGEKPYQCKECGKAFNRSSTLTQHRRIHTGEKPYECVECGKTFIT 411

  Fly   268 ISHLMTHLSSNIHKR 282
            .||...||.::..:|
Human   412 SSHRSKHLKTHSGER 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071
		C2H2 Zn finger	144..164	CDD:275368	8/19 (42%)
		C2H2 Zn finger	172..194	CDD:275368	7/21 (33%)
		zf-H2C2_2	186..211	CDD:290200	12/24 (50%)
		UFD2	<256..>294	CDD:227443	9/27 (33%)
		C2H2 Zn finger	258..280	CDD:275368	8/21 (38%)
ZNF562	NP_001123503.1	KRAB	40..81	CDD:307490
		COG5048	<117..308	CDD:227381	9/23 (39%)
		C2H2 Zn finger	181..198	CDD:275370
		C2H2 Zn finger	206..226	CDD:275368
		COG5048	<258..420	CDD:227381	50/137 (36%)
		C2H2 Zn finger	263..282	CDD:275368
		C2H2 Zn finger	290..310	CDD:275368	8/19 (42%)
		C2H2 Zn finger	318..338	CDD:275368	7/21 (33%)
		C2H2 Zn finger	346..366	CDD:275368	5/19 (26%)
		C2H2 Zn finger	374..394	CDD:275368	7/19 (37%)
		C2H2 Zn finger	402..422	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050