DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6813 and CG31365

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_732827.1	Gene:	CG31365 / 42736	FlyBaseID:	FBgn0051365	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	291	Identity:	78/291 - (26%)
Similarity:	119/291 - (40%)	Gaps:	49/291 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 NGHLVRQIHSITGVELSCKKEISGQMCTTCLDNLQAAIKFRQRCIIAEKQNLERIECDSKDCSTD 87
            :|....:|..:  |..:..:|||.:         |....|.:..||.||:..:|.|       ..
  Fly   370 SGEKPEEIEDV--VVFNLGEEISQE---------QQVFSFHENVIIVEKEQNDRDE-------QT 416

  Fly    88 PIIYEDIDDNQIESEL--DESILCPEVKDLPMPSAEK--------VSAPTSL-------NHQKSI 135
            |:      ..:..|||  .:...||:.|...:....|        |:.||..       .|.|.:
  Fly   417 PL------KRKRSSELVFKQESSCPQPKTGRITDTVKSFQCHLCPVAFPTQKLLTRHHNTHIKGL 475

  Fly   136 GGGTGPYV-CPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRIHTGEQP 199
            ..|.|..: ||.|...::..|:.:.|.:.|||:|.|.|  ..||.||:.|:.|..|...|||.:.
  Fly   476 KSGKGGTLKCPSCALQLSCASSLKRHMIIHTGLKPFKC--SECELSFSQREVLKRHMDTHTGVKR 538

  Fly   200 YVCVYCPRRFSSSGARQEH-HRRHR-NERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQ 262
            :.|..|...|:.....|:| .|.|. |.|.::|..|.:||.....|.:|.:.|.... ..|..|.
  Fly   539 HQCPQCSSCFAQKSNLQQHIGRVHMGNSRTHKCHLCHRSFNHVSGLSRHLVTHAGVM-FSCKQCG 602

  Fly   263 KHFKRISHLMTHLSSNIHKRKEEKLTELAIE 293
            :.|...|.:..|::: :||.| .|||:...|
  Fly   603 RQFNDRSAVQRHVTT-MHKVK-NKLTDYISE 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	12/52 (23%)
		C2H2 Zn finger	144..164	CDD:275368	5/19 (26%)
		C2H2 Zn finger	172..194	CDD:275368	8/21 (38%)
		zf-H2C2_2	186..211	CDD:290200	8/24 (33%)
		UFD2	<256..>294	CDD:227443	12/38 (32%)
		C2H2 Zn finger	258..280	CDD:275368	5/21 (24%)
CG31365	NP_732827.1	zf-AD	13..86	CDD:214871
		vATP-synt_E	109..>244	CDD:304907
		RRF	<161..222	CDD:294170
		zf-C2H2_8	454..530	CDD:292531	24/77 (31%)
		C2H2 Zn finger	485..505	CDD:275368	5/19 (26%)
		zf-H2C2_2	497..522	CDD:290200	11/26 (42%)
		C2H2 Zn finger	513..533	CDD:275368	8/21 (38%)
		zf-H2C2_2	526..550	CDD:290200	8/23 (35%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	571..591	CDD:275368	6/19 (32%)
		C2H2 Zn finger	598..617	CDD:275368	5/18 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050