DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG6813 and CG6689

DIOPT Version :9

Sequence 1:NP_001163590.1 Gene:CG6813 / 41396 FlyBaseID:FBgn0037923 Length:294 Species:Drosophila melanogaster
Sequence 2:NP_650051.1 Gene:CG6689 / 41345 FlyBaseID:FBgn0037877 Length:613 Species:Drosophila melanogaster


Alignment Length:445 Identity:99/445 - (22%)
Similarity:139/445 - (31%) Gaps:170/445 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 CRIC----SRSDAPIDLFGPGNGHLVRQIHSITGVELSCKKEISGQMCTTCLDNLQAAIKFRQRC 66
            ||.|    :......|||.|.|..|:..|..|:||.:|.|.:....||..|...|..||.||:.|
  Fly   167 CRTCYNDFTADFRAKDLFDPANSVLLFHIEVISGVWISHKPDEPRLMCPACKSALDQAIDFREMC 231

  Fly    67 II----------------------------------AEKQNLERIECDSKDCSTDPIIYEDIDDN 97
            |.                                  .|..|:|.||    |...|.:..|...|:
  Fly   232 ISTELKLSQAKPSTDEVQIEAENENPISSDHDLISDTENTNVEEIE----DAGGDHVEDEATSDD 292

  Fly    98 QIESE-LDESILCPEVKDLPM----------------------------PSAEKVSAPTSLNHQK 133
            |...| :||....|..:| |:                            |.|.|..|......::
  Fly   293 QTSQEAVDEVAESPAAQD-PLSVALGAKIFKELLDQYTGKEKARLRKGAPIASKPKAKEKAAGEQ 356

  Fly   134 SIGGGTGP--------------------YVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCE 178
            .......|                    :||..||:......|.:.|.||||..||:.|.  .|.
  Fly   357 KPKRSANPKTKEERNLIRRAQLRAKPPNFVCDQCGQAFRMSHNLRIHMLRHTRTKNYQCT--ECP 419

  Fly   179 RSFATRKELTSHTRI-HTGEQPYVCVYCPRRFSSSGARQEHH----------------------- 219
            ::|........|.|| |.||.|:.|.:|...|:..||||:|.                       
  Fly   420 KTFYDAYMRNMHIRIRHRGETPFACGFCSETFAYPGARQKHESEVHNAAPRLIVKRINPKPMPKP 484

  Fly   220 -------------------------------------------------RRH---RNERRYECDT 232
                                                             :||   ..:|..:||.
  Fly   485 RESVRYQCKLCQKHYASKYALGWHIKSHTDANAYKCQRCSKSYSDPNKLKRHEMTHEKRPLQCDV 549

  Fly   233 CKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSSNIHKRKEEKL 287
            |.|.|.....||:|::||...|.::|.||..:|:...::.:|.:|.:|:....||
  Fly   550 CLKGFYQRTRLREHELIHTGERPYWCEVCNVNFRYKYNMKSHANSKMHQDNARKL 604

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6813NP_001163590.1 zf-AD 6..76 CDD:285071 27/107 (25%)
C2H2 Zn finger 144..164 CDD:275368 6/19 (32%)
C2H2 Zn finger 172..194 CDD:275368 6/22 (27%)
zf-H2C2_2 186..211 CDD:290200 10/25 (40%)
UFD2 <256..>294 CDD:227443 9/32 (28%)
C2H2 Zn finger 258..280 CDD:275368 6/21 (29%)
CG6689NP_650051.1 THAP 2..96 CDD:283206
zf-AD 167..240 CDD:214871 25/72 (35%)
zf-C2H2 385..407 CDD:278523 7/21 (33%)
C2H2 Zn finger 387..407 CDD:275368 6/19 (32%)
zf-H2C2_2 399..422 CDD:290200 10/24 (42%)
C2H2 Zn finger 415..436 CDD:275368 6/22 (27%)
C2H2 Zn finger 444..460 CDD:275368 7/15 (47%)
C2H2 Zn finger 492..512 CDD:275368 0/19 (0%)
C2H2 Zn finger 520..540 CDD:275368 2/19 (11%)
C2H2 Zn finger 547..567 CDD:275368 8/19 (42%)
zf-met 574..597 CDD:289631 6/22 (27%)
C2H2 Zn finger 575..591 CDD:275368 4/15 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 62 1.000 Inparanoid score I2531
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000724
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.960

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