DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6813 and ranshi

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster

Alignment Length:	335	Identity:	96/335 - (28%)
Similarity:	149/335 - (44%)	Gaps:	56/335 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRICSR---SDAPIDLFGPGNGHLVRQIHSITGVELSCKKEISGQMCTTCLDNLQAAIKFRQRCI 67
            ||.|.:   ::..:::|...|...:..|..:||..|.....:..::|.:|...||.||.||:||:
  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERCL 70

  Fly    68 IAEKQNL----------------------ERIECDSKDCSTDPIIYEDIDDNQIESE-------L 103
            ..:::.|                      |.:|.|..:.|.:....:|:::..|:|.       |
  Fly    71 EVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSGFKVEDIL 135

  Fly   104 DES------------ILCPEVKDLPMPSAEKVSA----------PTSLNHQKSIGGGTGPYVCPD 146
            :||            |...|:..|...|..:|.|          |....::::.......:.|.:
  Fly   136 NESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCEE 200

  Fly   147 CGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRIHTGEQPYVCVYCPRRFSS 211
            ||..|.::.:|..|..||.|:|.|.|.|  ||..|.|..||..|.|.||||:|:.|.:|.|.||.
  Fly   201 CGNHIKDRISFILHCKRHRGVKEFGCEF--CEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSD 263

  Fly   212 SGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLS 276
            ...|.:|.|.|.|||.:.|..|..:|.:|..|:.|.::|...:...|.:|.|.|.|.:||.||..
  Fly   264 YSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYR 328

  Fly   277 SNIHKRKEEK 286
            ||.|:|..:|
  Fly   329 SNAHRRNMQK 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	20/94 (21%)
		C2H2 Zn finger	144..164	CDD:275368	6/19 (32%)
		C2H2 Zn finger	172..194	CDD:275368	10/21 (48%)
		zf-H2C2_2	186..211	CDD:290200	13/24 (54%)
		UFD2	<256..>294	CDD:227443	14/31 (45%)
		C2H2 Zn finger	258..280	CDD:275368	11/21 (52%)
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	19/70 (27%)
		C2H2 Zn finger	198..218	CDD:275368	6/19 (32%)
		COG5048	222..>276	CDD:227381	26/55 (47%)
		C2H2 Zn finger	226..246	CDD:275368	10/21 (48%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	9/21 (43%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	7/23 (30%)
		C2H2 Zn finger	310..328	CDD:275368	9/17 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.060