DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6813 and nom

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001262384.1	Gene:	nom / 41038	FlyBaseID:	FBgn0037617	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	336	Identity:	97/336 - (28%)
Similarity:	151/336 - (44%)	Gaps:	57/336 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRILNCRICSRS---DAPIDLFGPGNGHLVRQIHSITGVELSCKKEISGQMCTTCLDNLQAAIKF 62
            |.|..||:|.||   ...::||.||...::|:|..|||:.|.........:|..|..:||:|:.|
  Fly     1 MLINVCRVCGRSRLCPKAVELFKPGRQDILRRIQLITGILLQQIPNAPDMVCFCCQTDLQSAMIF 65

  Fly    63 RQRCIIAEKQNLERIECDSKDCS-------TDPI------------------IYEDIDDNQIESE 102
            |::||:.:|:.:..::.|....|       .||.                  |.:.:..|:.::.
  Fly    66 RRQCILQQKKWVPLLQSDKVGASEEKKVEPNDPSTKKKTTKRRRGRPRMPLEIVDIVVTNESKAS 130

  Fly   103 LDESILCPE-------------------VKDLPMPSAEKVSAPTSLNHQKSIGGGTGPYVCPDCG 148
            ..||:...|                   ::::.:|..:.:.:...|.:.:.       :.|..||
  Fly   131 AGESVGGDEFDQPVEISNEPDATDSDVNLEEIDLPDEDGLESDHDLPNVQI-------HKCDTCG 188

  Fly   149 RIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRI-HTGEQPYVCVYCPRRFSSS 212
            .|.||||:...|...|.||:.:.|  ..|.::|....||.:|... ||.|.|:.|.||.||:.|.
  Fly   189 IIKNNKSSLVRHQFEHNGIRPYPC--KECPKTFLVASELKAHNLTHHTLEPPFACRYCDRRYFSV 251

  Fly   213 GARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSS 277
            ..|::|.|.|.|||.:.||.|.|:|..:..|:.|..:|...|.:.|.||.:.|....||.||..|
  Fly   252 VGRKKHERVHTNERPFVCDQCGKAFTRTCILKAHMAVHQVVRKYSCDVCDRSFSLKKHLATHFIS 316

  Fly   278 NIHKRKEEKLT 288
            |.|||..|.:|
  Fly   317 NTHKRNAEAVT 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	25/72 (35%)
		C2H2 Zn finger	144..164	CDD:275368	9/19 (47%)
		C2H2 Zn finger	172..194	CDD:275368	6/22 (27%)
		zf-H2C2_2	186..211	CDD:290200	12/25 (48%)
		UFD2	<256..>294	CDD:227443	15/33 (45%)
		C2H2 Zn finger	258..280	CDD:275368	10/21 (48%)
nom	NP_001262384.1	zf-AD	5..76	CDD:214871	25/70 (36%)
		C2H2 Zn finger	184..204	CDD:275368	9/19 (47%)
		C2H2 Zn finger	212..261	CDD:275368	19/50 (38%)
		zf-H2C2_2	255..278	CDD:290200	11/22 (50%)
		C2H2 Zn finger	269..289	CDD:275368	7/19 (37%)
		zf-H2C2_2	282..305	CDD:290200	7/22 (32%)
		C2H2 Zn finger	297..313	CDD:275368	6/15 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.060