DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6813 and Zif

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster

Alignment Length:	372	Identity:	89/372 - (23%)
Similarity:	143/372 - (38%)	Gaps:	87/372 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRIC-------SRSDAPIDLFGPGNGHLVRQIHSITGVELSCKKEISGQMCTTCLDNLQAAIKFR 63
            ||:|       .|.|...:........::.|:..::...|:.::.|...:|.:|...|..|.:||
  Fly    10 CRVCLAQSERLQRLDEIREEGEESPNEMLIQLLGVSYSNLNDREHIPDGICKSCKVELNMAYQFR 74

  Fly    64 QRCI---------------------------------------------------IAEKQNLERI 77
            ::.:                                                   ..||.:.|.:
  Fly    75 EKALRKQMEIEEYCRELGLLDESDVMMIKEEDGSQQQCDEEMYILEETTTGEEEHQEEKGHEEYL 139

  Fly    78 ECDSKD---CSTDPIIYEDIDDN---QIESELDESILCPEVKDLPMPS---AEKVSAPTSLNHQK 133
            |.|:.|   |..|.|.|  ::||   ::.|:..|.:|..|.:....||   |.:.:|..||..::
  Fly   140 EVDTSDQQECIGDTIEY--LEDNYTIEMNSDQTEIVLESEKQYEETPSQQLALQEAAKASLKARR 202

  Fly   134 ------------SIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKE 186
                        |.|...|.|:|..||.....:....||..||.||..:.|..  |:..|..|::
  Fly   203 GRVRRGLNSLTTSDGTEKGGYICDVCGNFYEKRGRMMEHRRRHDGICQYACEL--CDAKFQVREQ 265

  Fly   187 LTSHTRIHTGEQPYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHV 251
            |..|...|||.:||.|.:|.|:|......:.|...||..:.|.|..|.|:|..:..|.||::||.
  Fly   266 LRKHMYSHTGSKPYKCSFCSRQFFYESVLKSHENVHRGIKPYVCKVCDKAFAYAHSLTKHELIHS 330

  Fly   252 DARNHYCYVCQKHFKRISHLMTHLSSNIHKR----KEEKLTELAIEQ 294
            |.:.:.|..|.|.|:.:.|:..|..:.:|:.    .|....|:..||
  Fly   331 DIKLYRCDYCNKDFRLLHHMRQHEETKLHQNAVMLAESMKVEMVAEQ 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	16/127 (13%)
		C2H2 Zn finger	144..164	CDD:275368	5/19 (26%)
		C2H2 Zn finger	172..194	CDD:275368	6/21 (29%)
		zf-H2C2_2	186..211	CDD:290200	11/24 (46%)
		UFD2	<256..>294	CDD:227443	9/41 (22%)
		C2H2 Zn finger	258..280	CDD:275368	6/21 (29%)
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071	14/76 (18%)
		C2H2 Zn finger	225..245	CDD:275368	5/19 (26%)
		COG5048	<250..369	CDD:227381	37/120 (31%)
		C2H2 Zn finger	253..273	CDD:275368	6/21 (29%)
		zf-H2C2_2	266..288	CDD:290200	10/21 (48%)
		C2H2 Zn finger	281..301	CDD:275368	5/19 (26%)
		zf-H2C2_2	294..318	CDD:290200	8/23 (35%)
		C2H2 Zn finger	309..329	CDD:275368	7/19 (37%)
		C2H2 Zn finger	337..353	CDD:275368	5/15 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960