DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6813 and CG17359

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster

Alignment Length:	342	Identity:	89/342 - (26%)
Similarity:	142/342 - (41%)	Gaps:	74/342 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRIC-SRSDAPIDLFGP--GNGHLVRQIHSITGVELSCKKEISG-----------QMCTTCLDNL 56
            ||:| ..||..:|::..  .:.:.|::...:....|   :|.||           .:|..|.:.:
  Fly     7 CRVCRDESDCLLDIYTEPYASSNRVQEQEPVLATML---RECSGCSVHKEDGMPQFICVECAEAV 68

  Fly    57 QAAIKFRQRCIIAEKQNLERIECDSKDCSTDPIIY-EDIDDNQIESELDESIL----CPE----- 111
            :.|.:.|::| ....|..|::....|:  .|.|.| .:|.|| ||.::..|::    .||
  Fly    69 RNAYRLRRQC-RKSHQYFEQLRLMMKE--LDDIEYCLNIGDN-IEPQMPVSVMEAGKTPETSEPL 129

  Fly   112 ------VKDLPMPSAEKVSAPTSLNHQKSIGGGTGPYVCPDCGRIINNKSNFQ------------ 158
                  ||.:| |..:.:|:|...|::..:.....|...|      :|||..:
  Fly   130 LVELVQVKYMP-PEPKPISSPLPDNNEHKLAQSYSPAKTP------HNKSKRRARSYSDNDSWSP 187

  Fly   159 EHTLRHTG---IKN-------------FHCVFLNCERSFATRKELTSHTRIHTGEQPYVCVYCPR 207
            :..|.|..   |.|             :.|..  |.:||..::.|..|.||||||:||.|..|||
  Fly   188 DSELEHEDDDKIWNASKRGKPKRVPGPYRCKL--CTQSFTQKQNLEIHMRIHTGERPYKCSLCPR 250

  Fly   208 RFSSSGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLM 272
            .|:..|..|.|.|.|..||.:.|..|.|.|...|.|:.|...|...:...|..||:.||:::.|.
  Fly   251 SFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKCSKCQQSFKQLNGLQ 315

  Fly   273 THLSSNIHKRKEEKLTE 289
            .|:|::...::.....|
  Fly   316 KHMSAHTRGKRRTSSQE 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	17/83 (20%)
		C2H2 Zn finger	144..164	CDD:275368	5/31 (16%)
		C2H2 Zn finger	172..194	CDD:275368	7/21 (33%)
		zf-H2C2_2	186..211	CDD:290200	15/24 (63%)
		UFD2	<256..>294	CDD:227443	9/34 (26%)
		C2H2 Zn finger	258..280	CDD:275368	8/21 (38%)
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	18/84 (21%)
		zf-C2H2	215..237	CDD:278523	7/23 (30%)
		C2H2 Zn finger	217..237	CDD:275368	7/21 (33%)
		zf-H2C2_2	229..254	CDD:290200	15/24 (63%)
		C2H2 Zn finger	245..265	CDD:275368	9/19 (47%)
		zf-H2C2_2	257..282	CDD:290200	10/24 (42%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	7/23 (30%)
		C2H2 Zn finger	301..321	CDD:275368	8/19 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000