DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6813 and ZNF773

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_940944.1	Gene:	ZNF773 / 374928	HGNCID:	30487	Length:	442	Species:	Homo sapiens

Alignment Length:	157	Identity:	54/157 - (34%)
Similarity:	83/157 - (52%)	Gaps:	3/157 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 LNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRI 193
            :.||: :..|..||.|.:||::.::|||...|.:.|||.:.:.|  .:|.:||:...:|..|.|:
Human   207 VQHQR-LHTGEKPYECSECGKLFSHKSNLFIHQIVHTGERPYGC--SDCGKSFSRNADLIQHQRV 268

  Fly   194 HTGEQPYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYC 258
            ||||:|:.|..|.:.|..:....:|||.|...|.|||..|.|.|..:..|.||:.:|...|.:.|
Human   269 HTGEKPFTCSECGKAFRHNSTLVQHHRIHTGVRPYECSECGKLFSFNSSLMKHQRVHTGERPYKC 333

  Fly   259 YVCQKHFKRISHLMTHLSSNIHKRKEE 285
            ..|.|.:...|.|:.|...:..:|..|
Human   334 SECGKFYSHKSSLINHWRVHTGERPYE 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071
		C2H2 Zn finger	144..164	CDD:275368	7/19 (37%)
		C2H2 Zn finger	172..194	CDD:275368	7/21 (33%)
		zf-H2C2_2	186..211	CDD:290200	11/24 (46%)
		UFD2	<256..>294	CDD:227443	8/30 (27%)
		C2H2 Zn finger	258..280	CDD:275368	6/21 (29%)
ZNF773	NP_940944.1	KRAB	15..75	CDD:214630
		KRAB	15..54	CDD:279668
		C2H2 Zn finger	153..169	CDD:275368
		C2H2 Zn finger	193..213	CDD:275368	2/6 (33%)
		zf-H2C2_2	206..230	CDD:290200	8/23 (35%)
		COG5048	<209..438	CDD:227381	54/155 (35%)
		C2H2 Zn finger	221..241	CDD:275368	7/19 (37%)
		C2H2 Zn finger	249..269	CDD:275368	7/21 (33%)
		zf-H2C2_2	261..286	CDD:290200	11/24 (46%)
		C2H2 Zn finger	277..297	CDD:275368	6/19 (32%)
		C2H2 Zn finger	305..325	CDD:275368	7/19 (37%)
		zf-H2C2_2	317..342	CDD:290200	8/24 (33%)
		C2H2 Zn finger	333..353	CDD:275368	6/19 (32%)
		C2H2 Zn finger	361..381	CDD:275368	54/157 (34%)
		zf-H2C2_2	373..397	CDD:290200
		C2H2 Zn finger	389..409	CDD:275368
		zf-H2C2_2	401..426	CDD:290200
		C2H2 Zn finger	417..437	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050