DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6813 and ZSCAN22

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001308045.1	Gene:	ZSCAN22 / 342945	HGNCID:	4929	Length:	491	Species:	Homo sapiens

Alignment Length:	172	Identity:	64/172 - (37%)
Similarity:	88/172 - (51%)	Gaps:	11/172 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 CPEVKDLPMPSAEKVSAPTSLNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCV 173
            |.|.:.: ..||..:.|     |||:....| ||.|.:||:..:..::..:|.:.|||.|...|
Human   270 CRECRKM-FQSASALEA-----HQKTHSRKT-PYACSECGKAFSRSTHLAQHQVVHTGAKPHEC- 326

  Fly   174 FLNCERSFATRKELTSHTRIHTGEQPYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFV 238
             ..|.::|:....||.|.||||||:||.|..|.:.||.|....:|.|.|..||.||||.|.|:|.
Human   327 -KECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFS 390

  Fly   239 SSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSSNIH 280
            .|..|.:|:.||...:.:.|..|.:.|...|.|:.||  .||
Human   391 QSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHL--RIH 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071
		C2H2 Zn finger	144..164	CDD:275368	4/19 (21%)
		C2H2 Zn finger	172..194	CDD:275368	7/21 (33%)
		zf-H2C2_2	186..211	CDD:290200	14/24 (58%)
		UFD2	<256..>294	CDD:227443	9/25 (36%)
		C2H2 Zn finger	258..280	CDD:275368	7/21 (33%)
ZSCAN22	NP_001308045.1	SCAN	45..133	CDD:307924
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	134..161
		COG5048	<174..482	CDD:227381	64/172 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	204..249
		C2H2 Zn finger	270..290	CDD:275368	8/25 (32%)
		C2H2 Zn finger	298..318	CDD:275368	4/19 (21%)
		C2H2 Zn finger	326..346	CDD:275368	7/21 (33%)
		C2H2 Zn finger	354..374	CDD:275368	7/19 (37%)
		C2H2 Zn finger	382..402	CDD:275368	8/19 (42%)
		C2H2 Zn finger	410..430	CDD:275368	7/21 (33%)
		C2H2 Zn finger	438..458	CDD:275368
		C2H2 Zn finger	466..486	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960