DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6813 and ZNF517

DIOPT Version :9

Sequence 1:NP_001163590.1 Gene:CG6813 / 41396 FlyBaseID:FBgn0037923 Length:294 Species:Drosophila melanogaster
Sequence 2:NP_001371833.1 Gene:ZNF517 / 340385 HGNCID:27984 Length:492 Species:Homo sapiens


Alignment Length:199 Identity:63/199 - (31%)
Similarity:83/199 - (41%) Gaps:21/199 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    92 EDIDDNQIESELDESILCPEV--KDLPMPSAEKVSAP--------------TSLNHQKSIGGGTG 140
            ||..|........|....|.|  :||..|...  |||              ..|.|| .|..|..
Human   142 EDGSDKPTHPRAREHSASPRVLQEDLGRPVGS--SAPRYRCVCGKAFRYNSLLLRHQ-IIHTGAK 203

  Fly   141 PYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRIHTGEQPYVCVYC 205
            |:.|.:||:.....|....|.|.||..|.|.|.  .|.::|....:|.:|.|:||.|:||.|..|
Human   204 PFQCTECGKAFKQSSILLRHQLIHTEEKPFQCG--ECGKAFRQSTQLAAHHRVHTRERPYACGEC 266

  Fly   206 PRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISH 270
            .:.||.|....:|.:.|..|:.:.|..|.|:|.....|.:|..||...|.:.|..|.:.|.|.|.
Human   267 GKAFSRSSRLLQHQKFHTGEKPFACTECGKAFCRRFTLNEHGRIHSGERPYRCLRCGQRFIRGSS 331

  Fly   271 LMTH 274
            |:.|
Human   332 LLKH 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6813NP_001163590.1 zf-AD 6..76 CDD:285071
C2H2 Zn finger 144..164 CDD:275368 6/19 (32%)
C2H2 Zn finger 172..194 CDD:275368 6/21 (29%)
zf-H2C2_2 186..211 CDD:290200 11/24 (46%)
UFD2 <256..>294 CDD:227443 7/19 (37%)
C2H2 Zn finger 258..280 CDD:275368 7/17 (41%)
ZNF517NP_001371833.1 KRAB 14..73 CDD:214630
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 129..170 8/27 (30%)
C2H2 Zn finger 180..199 CDD:275368 3/19 (16%)
COG5048 <203..342 CDD:227381 46/135 (34%)
C2H2 Zn finger 207..227 CDD:275368 6/19 (32%)
C2H2 Zn finger 235..255 CDD:275368 6/21 (29%)
C2H2 Zn finger 263..283 CDD:275368 6/19 (32%)
COG5048 <287..459 CDD:227381 16/49 (33%)
C2H2 Zn finger 291..311 CDD:275368 6/19 (32%)
C2H2 Zn finger 319..339 CDD:275368 7/17 (41%)
C2H2 Zn finger 370..390 CDD:275368
C2H2 Zn finger 398..418 CDD:275368
C2H2 Zn finger 426..446 CDD:275368
C2H2 Zn finger 454..474 CDD:275368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 472..492
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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