DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6813 and Cf2

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster

Alignment Length:	362	Identity:	76/362 - (20%)
Similarity:	122/362 - (33%)	Gaps:	125/362 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRICSRSDAPIDLFGPGNGHLVRQIHSITGVELSCKKEISGQMCTTC---------LDNLQAAI- 60
            |.:||       ::|         |||.|......|....|.:|||.         ::..:||:
  Fly   157 CLMCS-------IYG---------IHSATQQPNEYKCTQCGSICTTAMLAAGQQGFMEQQEAAVT 205

  Fly    61 -------------------KFRQRCIIAE--------------KQNLERIECDSKDCSTDPIIYE 92
                               :..|:.:.||              :|..|.:|...::      :.|
  Fly   206 PDDQLPAMAPRDMRLTPEEQHHQQQLQAEHHHQQQHQQQQQQQQQQQELLEQQQRE------MQE 264

  Fly    93 DIDDNQIESELDESILCPEVKDLPMPSAEKVSAPTSLNHQKSIGGGT-----------GPYVCPD 146
            .....|:.....:..|..:...|.:|       |.::...|:..||.           .|....|
  Fly   265 QAQQQQVHHHQQDQDLAGDQVALKVP-------PLTVKLNKNANGGAIVSHPQVIIKEEPLSLSD 322

  Fly   147 CGRIINNKSNFQ--------------------------EHTLRHTGIKNFHCVFLNCERSFATRK 185
            .|.::|:...:.                          .|.:||      .|.  :|.::|.|..
  Fly   323 SGDVVNSVPVYAIQANPGVPAPASSGVLVGTQTVPADLAHKIRH------KCP--DCPKTFKTPG 379

  Fly   186 ELTSHTRIHTG-------EQPYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSSGCL 243
            .|..|.:||||       |:||.|.||.:.|:.|...::|.|.|..|:.:.|..|:|||.....|
  Fly   380 TLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFHCGYCEKSFSVKDYL 444

  Fly   244 RKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSSNIH 280
            .||...|...:.:.|..|.|.|.:.|.|..| ::.:|
  Fly   445 TKHIRTHTGEKPYTCPYCDKRFTQRSALTVH-TTKLH 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	19/112 (17%)
		C2H2 Zn finger	144..164	CDD:275368	4/45 (9%)
		C2H2 Zn finger	172..194	CDD:275368	6/21 (29%)
		zf-H2C2_2	186..211	CDD:290200	13/31 (42%)
		UFD2	<256..>294	CDD:227443	8/25 (32%)
		C2H2 Zn finger	258..280	CDD:275368	7/21 (33%)
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	37/114 (32%)
		C2H2 Zn finger	368..388	CDD:275368	6/21 (29%)
		C2H2 Zn finger	403..423	CDD:275368	7/19 (37%)
		C2H2 Zn finger	431..451	CDD:275368	8/19 (42%)
		zf-H2C2_2	443..468	CDD:316026	8/24 (33%)
		C2H2 Zn finger	459..480	CDD:275368	7/21 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468421
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030