DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6813 and ZSCAN23

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001012458.1	Gene:	ZSCAN23 / 222696	HGNCID:	21193	Length:	389	Species:	Homo sapiens

Alignment Length:	293	Identity:	76/293 - (25%)
Similarity:	118/293 - (40%)	Gaps:	49/293 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LVRQIHSITGVELSC----KKEISGQMCTTCLDNLQAAIKFRQRCIIAEKQNLERIECDSKDCST 86
            ::.|..:|...||..    .:.:||:...|.|::|:..:......:::.....|..   .|:.:|
Human    92 VLEQFLTILPEELQAWVRQHRPVSGEEAVTVLEDLERELDDPGEQVLSHAHEQEEF---VKEKAT 153

  Fly    87 DPIIYEDIDD--NQIESELDESI--LCP-----------------------EVKDL--------- 115
            .....|..:|  ..:|.:|..::  :||                       |||.|
Human   154 PGAAQESSNDQFQTLEEQLGYNLREVCPVQEIDGKAGTWNVELAPKREISQEVKSLIQVLGKQNG 218

  Fly   116 ---PMPS-AEKVSAPTSLNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLN 176
               .:|. .:.......|..|:.......||:|.:||:.....|...||...|||.|.:.|.  .
Human   219 NITQIPEYGDTCDREGRLEKQRVSSSVERPYICSECGKSFTQNSILIEHQRTHTGEKPYECD--E 281

  Fly   177 CERSFATRKELTSHTRIHTGEQPYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSSG 241
            |.|:|:.|..|..|.|:||||:.|.|..|.:.||.:.....|.|.|..|:.|:|:.|.|||....
Human   282 CGRAFSQRSGLFQHQRLHTGEKRYQCSVCGKAFSQNAGLFHHLRIHTGEKPYQCNQCNKSFSRRS 346

  Fly   242 CLRKHKMIHVDARNHYCYVCQKHFKRISHLMTH 274
            .|.||:.||...|.:.|..|.|:|....:|:.|
Human   347 VLIKHQRIHTGERPYECEECGKNFIYHCNLIQH 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	9/53 (17%)
		C2H2 Zn finger	144..164	CDD:275368	6/19 (32%)
		C2H2 Zn finger	172..194	CDD:275368	8/21 (38%)
		zf-H2C2_2	186..211	CDD:290200	11/24 (46%)
		UFD2	<256..>294	CDD:227443	6/19 (32%)
		C2H2 Zn finger	258..280	CDD:275368	6/17 (35%)
ZSCAN23	NP_001012458.1	SCAN	44..156	CDD:128708	12/66 (18%)
		SCAN	45..132	CDD:280241	9/39 (23%)
		COG5048	<215..384	CDD:227381	54/167 (32%)
		zf-C2H2	249..271	CDD:278523	7/21 (33%)
		C2H2 Zn finger	251..271	CDD:275368	6/19 (32%)
		zf-H2C2_2	264..288	CDD:290200	10/25 (40%)
		C2H2 Zn finger	279..299	CDD:275368	8/21 (38%)
		zf-H2C2_2	292..316	CDD:290200	11/23 (48%)
		C2H2 Zn finger	307..327	CDD:275368	6/19 (32%)
		zf-H2C2_2	323..344	CDD:290200	10/20 (50%)
		C2H2 Zn finger	335..355	CDD:275368	8/19 (42%)
		zf-H2C2_2	348..372	CDD:290200	10/23 (43%)
		C2H2 Zn finger	363..383	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050