DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6813 and ZSCAN25

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001337908.1	Gene:	ZSCAN25 / 221785	HGNCID:	21961	Length:	544	Species:	Homo sapiens

Alignment Length:	161	Identity:	52/161 - (32%)
Similarity:	82/161 - (50%)	Gaps:	7/161 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 LNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRI 193
            :.||:: ..|..||||.:|.:..:.:.:.:.|...|||.|.:.|.  :|.:||:.|:.|..|.|.
Human   391 MKHQRT-HLGKRPYVCSECWKTFSQRHHLEVHQRSHTGEKPYKCG--DCWKSFSRRQHLQVHRRT 452

  Fly   194 HTGEQPYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYC 258
            ||||:||.| .|.:.||.:.....|.|.|..|:.|.|..|.|.|.....|.:|:.||...:.::|
Human   453 HTGEKPYTC-ECGKSFSRNANLAVHRRAHTGEKPYGCQVCGKRFSKGERLVRHQRIHTGEKPYHC 516

  Fly   259 YVCQKHFKRISHLMTHLSSNIHKRKEEKLTE 289
            ..|.:.|.:.|.|..|..:   :.::|.|.:
Human   517 PACGRSFNQRSILNRHQKT---QHRQEPLVQ 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071
		C2H2 Zn finger	144..164	CDD:275368	3/19 (16%)
		C2H2 Zn finger	172..194	CDD:275368	8/21 (38%)
		zf-H2C2_2	186..211	CDD:290200	12/24 (50%)
		UFD2	<256..>294	CDD:227443	8/34 (24%)
		C2H2 Zn finger	258..280	CDD:275368	6/21 (29%)
ZSCAN25	NP_001337908.1	SCAN	38..136	CDD:322011
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	157..189
		KRAB_A-box	231..>259	CDD:143639
		COG5048	<324..532	CDD:227381	49/144 (34%)
		C2H2 Zn finger	350..370	CDD:275368
		C2H2 Zn finger	377..397	CDD:275368	2/6 (33%)
		C2H2 Zn finger	405..425	CDD:275368	3/19 (16%)
		C2H2 Zn finger	433..453	CDD:275368	8/21 (38%)
		C2H2 Zn finger	461..480	CDD:275368	6/19 (32%)
		C2H2 Zn finger	488..508	CDD:275368	6/19 (32%)
		C2H2 Zn finger	516..535	CDD:275368	6/18 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050