DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6813 and ZNF584

DIOPT Version :9

Sequence 1:NP_001163590.1 Gene:CG6813 / 41396 FlyBaseID:FBgn0037923 Length:294 Species:Drosophila melanogaster
Sequence 2:NP_775819.1 Gene:ZNF584 / 201514 HGNCID:27318 Length:421 Species:Homo sapiens


Alignment Length:279 Identity:74/279 - (26%)
Similarity:111/279 - (39%) Gaps:72/279 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    63 RQRCIIAEKQNLERIECDSKDCSTDPIIYEDIDDNQIESELDESILCPEVKDLPMPSAEKVSAPT 127
            :|...:|||    ..:|  .||....:....:.|:.|....:....||..:     ||.|.||  
Human   149 QQEVHVAEK----LFKC--SDCGKVFLKAFALLDHLITHSEERPFRCPTGR-----SAFKKSA-- 200

  Fly   128 SLNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTR 192
            .:|.:| |..|...:||.:||:..:..|..::|...|||||.|.|  .:|.::|..:..|..|.|
Human   201 HINPRK-IHTGETAHVCNECGKAFSYPSKLRKHQKVHTGIKPFKC--SDCGKTFNRKDALVLHQR 262

  Fly   193 IHTGEQPYVCVYCPRRFS---------------------------------------SSGAR--- 215
            |||||:||.|..|.:.||                                       .:|.|   
Human   263 IHTGERPYECSKCGKTFSVLSTLIRHRKVHIGERPYECTECGKFFKYNNSFILHQRVHTGERPFE 327

  Fly   216 --------------QEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFK 266
                          .:|.:.|..||.|||..|.|:|.:.....:|:..|.:.|::.|..|.|.||
Human   328 CKQCGKGYVTRSGLYQHWKVHTGERPYECSLCGKTFTTRSYRNRHQQFHTEERSYECTECGKAFK 392

  Fly   267 RISHLMTHLSSNIHKRKEE 285
            ..|.|:.|...:..:|::|
Human   393 HSSTLLQHKKVHTPERRQE 411

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6813NP_001163590.1 zf-AD 6..76 CDD:285071 4/12 (33%)
C2H2 Zn finger 144..164 CDD:275368 5/19 (26%)
C2H2 Zn finger 172..194 CDD:275368 6/21 (29%)
zf-H2C2_2 186..211 CDD:290200 14/63 (22%)
UFD2 <256..>294 CDD:227443 10/30 (33%)
C2H2 Zn finger 258..280 CDD:275368 8/21 (38%)
ZNF584NP_775819.1 KRAB 17..77 CDD:214630
KRAB 17..56 CDD:279668
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 120..146
C2H2 Zn finger 161..181 CDD:275368 5/21 (24%)
COG5048 <189..374 CDD:227381 53/194 (27%)
zf-C2H2 214..236 CDD:278523 6/21 (29%)
C2H2 Zn finger 216..236 CDD:275368 5/19 (26%)
zf-H2C2_2 229..253 CDD:290200 10/25 (40%)
C2H2 Zn finger 244..264 CDD:275368 6/21 (29%)
zf-H2C2_2 256..280 CDD:290200 12/23 (52%)
C2H2 Zn finger 272..292 CDD:275368 4/19 (21%)
zf-H2C2_2 285..309 CDD:290200 0/23 (0%)
C2H2 Zn finger 300..320 CDD:275368 0/19 (0%)
zf-H2C2_2 316..337 CDD:290200 2/20 (10%)
C2H2 Zn finger 328..348 CDD:275368 1/19 (5%)
C2H2 Zn finger 356..376 CDD:275368 5/19 (26%)
zf-H2C2_2 370..393 CDD:290200 7/22 (32%)
C2H2 Zn finger 384..404 CDD:275368 8/19 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 402..421 2/10 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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