DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6813 and ZNF582

DIOPT Version :9

Sequence 1:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001307300.2	Gene:	ZNF582 / 147948	HGNCID:	26421	Length:	517	Species:	Homo sapiens

Alignment Length:	172	Identity:	61/172 - (35%)
Similarity:	88/172 - (51%)	Gaps:	12/172 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 EVKDLPMPSAEKVSAPTS--LNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCV 173
            |.||     .||..:.:|  :.||:: ..|..||.|.:||:..|..|:.:.|...|||.|.:.|
Human   256 ECKD-----CEKAFSRSSQLIEHQRT-HTGEKPYQCKECGKAFNRISHLKVHYRIHTGEKPYAC- 313

  Fly   174 FLNCERSFATRKELTSHTRIHTGEQPYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFV 238
             ..|.::|:.|.:|..|..:|||.:.|.|..|.:.|:.......|.|.|..|:.|||..|.|:|.
Human   314 -KECGKTFSHRSQLIQHQTVHTGRKLYECKECGKAFNQGSTLIRHQRIHTGEKPYECKVCGKAFR 377

  Fly   239 SSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSSNIH 280
            .|..|::|:.||...:.:.|.||.:.|||:|||..|.  .||
Human   378 VSSQLKQHQRIHTGEKPYQCKVCGRAFKRVSHLTVHY--RIH 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071
		C2H2 Zn finger	144..164	CDD:275368	6/19 (32%)
		C2H2 Zn finger	172..194	CDD:275368	6/21 (29%)
		zf-H2C2_2	186..211	CDD:290200	9/24 (38%)
		UFD2	<256..>294	CDD:227443	12/25 (48%)
		C2H2 Zn finger	258..280	CDD:275368	10/21 (48%)
ZNF582	NP_001307300.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050