DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6813 and ZNF263

DIOPT Version :9

Sequence 1:NP_001163590.1 Gene:CG6813 / 41396 FlyBaseID:FBgn0037923 Length:294 Species:Drosophila melanogaster
Sequence 2:NP_005732.2 Gene:ZNF263 / 10127 HGNCID:13056 Length:683 Species:Homo sapiens


Alignment Length:281 Identity:78/281 - (27%)
Similarity:103/281 - (36%) Gaps:51/281 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 TGVELSCKKEISGQ---MCTTCLDNLQAAIKFRQRCIIAEKQNLERIE--CDSKDCSTDPIIYED 93
            :|.||...||:..:   :|..|..|      |.....:...|.:...|  |...||:      |.
Human   362 SGRELGRPKELQPKKLHLCPLCGKN------FSNNSNLIRHQRIHAAERLCMGVDCT------EI 414

  Fly    94 IDDNQIESELDESILCPEVKDLPMPSAEKVSAPTSLNHQKSIGGGTGPYVCPDCGRIINNKSNFQ 158
            ...|.....|..:.|..|.... :...:..|..|.|...:....|..||.|..||:..:..||..
Human   415 FGGNPRFLSLHRAHLGEEAHKC-LECGKCFSQNTHLTRHQRTHTGEKPYQCNICGKCFSCNSNLH 478

  Fly   159 EHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRIHTGEQPYVCVYCPRRFSSSGARQEHHRRHR 223
            .|...|||.|.:.|.  .|...||....|..|.||||||:||.|..|.:.||.|.....|.|.|.
Human   479 RHQRTHTGEKPYKCP--ECGEIFAHSSNLLRHQRIHTGERPYKCPECGKSFSRSSHLVIHERTHE 541

  Fly   224 NERRY-----------------------------ECDTCKKSFVSSGCLRKHKMIHVDARNHYCY 259
            .||.|                             ||.||.|||.....|.:|:..|...:.:.|.
Human   542 RERLYPFSECGEAVSDSTPFLTNHGAHKAEKKLFECLTCGKSFRQGMHLTRHQRTHTGEKPYKCT 606

  Fly   260 VCQKHFKRISHLMTHLSSNIH 280
            :|.::|...|:|:.|  ..||
Human   607 LCGENFSHRSNLIRH--QRIH 625

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6813NP_001163590.1 zf-AD 6..76 CDD:285071 10/44 (23%)
C2H2 Zn finger 144..164 CDD:275368 6/19 (32%)
C2H2 Zn finger 172..194 CDD:275368 7/21 (33%)
zf-H2C2_2 186..211 CDD:290200 13/24 (54%)
UFD2 <256..>294 CDD:227443 8/25 (32%)
C2H2 Zn finger 258..280 CDD:275368 6/21 (29%)
ZNF263NP_005732.2 SCAN 38..149 CDD:128708
Dendrin <128..>347 CDD:317849
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 147..185
KRAB 218..277 CDD:214630
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 230..301
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 322..368 3/5 (60%)
C2H2 Zn finger 380..400 CDD:275368 5/25 (20%)
zf-C2H2 380..400 CDD:306579 5/25 (20%)
COG5048 <434..649 CDD:227381 59/197 (30%)
C2H2 Zn finger 436..456 CDD:275368 3/20 (15%)
C2H2 Zn finger 464..484 CDD:275368 6/19 (32%)
C2H2 Zn finger 492..512 CDD:275368 7/21 (33%)
C2H2 Zn finger 520..540 CDD:275368 7/19 (37%)
C2H2 Zn finger 577..597 CDD:275368 8/19 (42%)
C2H2 Zn finger 605..625 CDD:275368 6/21 (29%)
COG5048 629..>682 CDD:227381
C2H2 Zn finger 633..653 CDD:275368
C2H2 Zn finger 661..681 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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