DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14711 and CMR3

DIOPT Version :9

Sequence 1:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_015338.1	Gene:	CMR3 / 856123	SGDID:	S000006217	Length:	317	Species:	Saccharomyces cerevisiae

Alignment Length:	306	Identity:	59/306 - (19%)
Similarity:	114/306 - (37%)	Gaps:	90/306 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 AMAPLFDDN-----DAQCRELVRKIEEVGSIKLVPLQNIPSMLCYSCVERLTSAHKFRELCQESE 78
            ::.|.|::|     |::.:...:::.:  |:.:||:.|    ..|:.:....::.::.....||:
Yeast    79 SLLPNFENNTPPNVDSRVQFPPQQVYQ--SMNVVPIVN----EIYTPISMNATSDQYPIYYTESQ 137

  Fly    79 RTFATNVVKAEMKSEPTDEVPHVVAD-------NIEYIYESANDFIDGVEDDIGMENIMEEPLED 136
            :..            |..:.||:.:.       .:..:|:....:      |.....|..||...
Yeast   138 QPI------------PHSQSPHLTSSAPLMMPVMVPTVYKPLTPY------DKEPITIASEPNFT 184

  Fly   137 GVGETSQAYETSTVVDDLDEDDLLVPNSTDSDYQPIERCRKAKVRKTRMTKRGRGRPRGASSGHP 201
            .:...|.......:..|.       |.|....|..:...::|...:|      :..| ||.....
Yeast   185 AISMASHPNAALELCHDR-------PKSVPPGYGVLPTMQEASNGRT------KSEP-GAVLNGS 235

  Fly   202 RSFSEERPPVQASFKSSPEVSSTNI--MCEICGNIYSKRAALNIHMRRHMAEKPFKCEICSKSFA 264
            .:||:        :|:...:|||.:  .|.:||                        :|||:
Yeast   236 ATFSD--------WKTDTRISSTKLRKQCPVCG------------------------KICSR--- 265

  Fly   265 GPSELNRHIRVHTGEKPFLCKY--CNRSFADRSSNIRHERTHTNER 308
             ||.|..|..:|||:.||.|.:  |.:||..:|:.:||.::|..:|
Yeast   266 -PSTLKTHYLIHTGDTPFKCTWEGCTKSFNVKSNMLRHLKSHERKR 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071	11/66 (17%)
		C2H2 Zn finger	228..248	CDD:275368	3/19 (16%)
		zf-H2C2_2	240..264	CDD:290200	3/23 (13%)
		COG5048	249..>362	CDD:227381	21/62 (34%)
		C2H2 Zn finger	256..276	CDD:275368	7/19 (37%)
		zf-H2C2_2	268..292	CDD:290200	10/25 (40%)
		C2H2 Zn finger	284..304	CDD:275368	7/21 (33%)
		zf-H2C2_2	299..321	CDD:290200	4/10 (40%)
		C2H2 Zn finger	312..332	CDD:275368
		zf-H2C2_2	325..349	CDD:290200
		C2H2 Zn finger	340..362	CDD:275368
CMR3	NP_015338.1	COG5048	17..316	CDD:227381	59/306 (19%)
		C2H2 Zn finger	256..276	CDD:275370	10/47 (21%)
		C2H2 Zn finger	284..306	CDD:275370	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000