DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14711 and CG17806

DIOPT Version :9

Sequence 1:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	117/432 - (27%)
Similarity:	177/432 - (40%)	Gaps:	102/432 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LCRICLTEDINSEAMAPLFDDNDAQCRELVRKIEEVGSIKLVPLQNIPSMLCYSCVERLTSAHKF 70
            |||.|..|   :|....||   |.:.|:::..|.::....|.....:|:.:|.||:..|..|..|
  Fly     4 LCRTCGQE---AEHAKSLF---DKEARDVLSNILKLTGFWLRNQPGVPTRICLSCLLDLNDAIAF 62

  Fly    71 RELCQESERTFATNVVKAEMKSEPT-------------DEVPHVVAD-NIEYIYESANDFIDG-- 119
            ||.|..:..::.....|.|.....|             |.:|..:|. ....|....:..:||
  Fly    63 RERCIRTNSSWFEKQGKQEDSDTETAREGGNNRLESRVDVMPISIAQPQRRRILPQRSKKVDGVP 127

  Fly   120 ---VEDDIGMENIMEEPLEDGVGETSQAYETSTVVDDLD-EDDLLVPN--STDSDYQPIE----- 173
               ||..|....:.|.|..|             :||.|. ||.:.|.:  ...||| |:|
  Fly   128 LKTVETPIYPLVVPEIPPAD-------------LVDPLRCEDPIQVKSEPQLSSDY-PVESMNHE 178

  Fly   174 -------RCRKAKVRKTRM---TKRGRGRPRGASSGHPRSFSEERPPVQASFKSSPEV----SST 224
                   :..|.:.|..::   .::.|.:||.      :...||.|.     |...::    |:|
  Fly   179 EPASEMPQVMKEEPRTLQVIGEVQKNRRKPRS------KGCLEECPG-----KDMAKIENIDSTT 232

  Fly   225 N--------------------------IMCEICGNIYSKRAALNIHMRRHMAEKPFKCEICSKSF 263
            |                          ..|:.||..:|::...|:|:|||...|.|:|:.|.:..
  Fly   233 NKTKEEKYATRNKWGAAKRAYALEHRLYFCDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRME 297

  Fly   264 AGPSELNRHIRV-HTGEKPFLCKYCNRSFADRSSNIRHERTHTN---ERPFTCSTCGKAFSYSNV 324
            .....||.|:|: |.||.|::||||.:.|.:....:.|||.|..   .||..||||.|||..|..
  Fly   298 FTQHLLNLHVRIKHRGELPYVCKYCGKRFDNCLKRLNHERNHKESPVHRPHVCSTCQKAFKTSTA 362

  Fly   325 LKNHMLTHTGEKPFLCRVCNKTFSRKHQLDQHLGTMTHQQTV 366
            ||:|::.||||:||.|.:|...|:|::.|..|..:..|:..|
  Fly   363 LKDHIVVHTGEQPFHCELCQTFFNRRNALATHYKSKHHRLKV 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071	22/74 (30%)
		C2H2 Zn finger	228..248	CDD:275368	7/19 (37%)
		zf-H2C2_2	240..264	CDD:290200	9/23 (39%)
		COG5048	249..>362	CDD:227381	46/116 (40%)
		C2H2 Zn finger	256..276	CDD:275368	6/20 (30%)
		zf-H2C2_2	268..292	CDD:290200	12/24 (50%)
		C2H2 Zn finger	284..304	CDD:275368	8/19 (42%)
		zf-H2C2_2	299..321	CDD:290200	13/24 (54%)
		C2H2 Zn finger	312..332	CDD:275368	11/19 (58%)
		zf-H2C2_2	325..349	CDD:290200	12/23 (52%)
		C2H2 Zn finger	340..362	CDD:275368	6/21 (29%)
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071	22/77 (29%)
		zf-C2H2	260..282	CDD:278523	7/21 (33%)
		C2H2 Zn finger	262..282	CDD:275368	7/19 (37%)
		C2H2 Zn finger	290..311	CDD:275368	6/20 (30%)
		COG5048	<298..>383	CDD:227381	38/84 (45%)
		C2H2 Zn finger	319..339	CDD:275368	8/19 (42%)
		C2H2 Zn finger	350..370	CDD:275368	11/19 (58%)
		ZnF_U1	375..407	CDD:197732	10/30 (33%)
		C2H2 Zn finger	378..396	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960