DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14711 and CG6813

DIOPT Version :9

Sequence 1:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster

Alignment Length:	373	Identity:	100/373 - (26%)
Similarity:	142/373 - (38%)	Gaps:	101/373 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CRICLTEDINSEAMAPLFDDNDAQCRELVRKIEEVGSIKLVPLQNIPSMLCYSCVERLTSAHKFR 71
            ||||    ..|:|...||...:.   .|||:|..:..::|...:.|...:|.:|::.|.:|.|||
  Fly     6 CRIC----SRSDAPIDLFGPGNG---HLVRQIHSITGVELSCKKEISGQMCTTCLDNLQAAIKFR 63

  Fly    72 ELC-----QESERTFATNVVKAEMKSEPTDEVPHVVADNIEYIYESANDFIDGVEDDIGMENIME 131
            :.|     |..||      ::.:.|...||.:          |||..:|
  Fly    64 QRCIIAEKQNLER------IECDSKDCSTDPI----------IYEDIDD---------------- 96

  Fly   132 EPLEDGVGETSQAYETSTVVDDLDEDDLLVPNSTDSDYQPIERCRKAKVRKTRMTKRGRGRPRGA 196
                            :.:..:||| .:|.|...|   .|:....|...              ..
  Fly    97 ----------------NQIESELDE-SILCPEVKD---LPMPSAEKVSA--------------PT 127

  Fly   197 SSGHPRSFSEERPPVQASFKSSPEVSSTNIMCEICGNIYSKRAALNIHMRRHMAEKPFKCEI--C 259
            |..|.:|......|               .:|..||.|.:.::....|..||...|.|.|..  |
  Fly   128 SLNHQKSIGGGTGP---------------YVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNC 177

  Fly   260 SKSFAGPSELNRHIRVHTGEKPFLCKYCNRSFADRSSNIRHERTHTNERPFTCSTCGKAFSYSNV 324
            .:|||...||..|.|:||||:|::|.||.|.|:...:...|.|.|.|||.:.|.||.|:|..|..
  Fly   178 ERSFATRKELTSHTRIHTGEQPYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSSGC 242

  Fly   325 LKNHMLTHTGEKPFLCRVCNKTFSRKHQLDQHLGTMTHQQTVIHHKNE 372
            |:.|.:.|...:...|.||.|.|.|...|      |||..:.||.:.|
  Fly   243 LRKHKMIHVDARNHYCYVCQKHFKRISHL------MTHLSSNIHKRKE 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071	25/78 (32%)
		C2H2 Zn finger	228..248	CDD:275368	5/19 (26%)
		zf-H2C2_2	240..264	CDD:290200	8/25 (32%)
		COG5048	249..>362	CDD:227381	44/114 (39%)
		C2H2 Zn finger	256..276	CDD:275368	9/21 (43%)
		zf-H2C2_2	268..292	CDD:290200	13/23 (57%)
		C2H2 Zn finger	284..304	CDD:275368	7/19 (37%)
		zf-H2C2_2	299..321	CDD:290200	11/21 (52%)
		C2H2 Zn finger	312..332	CDD:275368	8/19 (42%)
		zf-H2C2_2	325..349	CDD:290200	8/23 (35%)
		C2H2 Zn finger	340..362	CDD:275368	8/21 (38%)
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	23/76 (30%)
		C2H2 Zn finger	144..164	CDD:275368	5/19 (26%)
		C2H2 Zn finger	172..194	CDD:275368	9/21 (43%)
		zf-H2C2_2	186..211	CDD:290200	14/24 (58%)
		UFD2	<256..>294	CDD:227443	13/35 (37%)
		C2H2 Zn finger	258..280	CDD:275368	10/27 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960