DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14711 and ouib

DIOPT Version :9

Sequence 1:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_649822.2	Gene:	ouib / 41039	FlyBaseID:	FBgn0037618	Length:	312	Species:	Drosophila melanogaster

Alignment Length:	373	Identity:	112/373 - (30%)
Similarity:	170/373 - (45%)	Gaps:	70/373 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MLCRICLTEDINSEAMAPLFDDNDAQCRELVRKIEEVGSIKLVPLQNIPSMLCYSCVERLTSAHK 69
            ::||:|..:.| .|....||   |...|:.::.:..:..::||.|.::|..:|..|...|.||..
  Fly     4 IVCRVCGRQKI-CEKSLNLF---DLVNRKYLKHLHMISGLRLVDLDDVPGFMCLCCQAELRSALA 64

  Fly    70 FRELCQESERTFATNVVKAEMKSEPTDEVPHVVADNIEYIYESA--NDFIDGVEDDIGMEN---- 128
            ||:||.:::..:.|    .|..|...||..:   ||.|...|..  :||....|.::..|.
  Fly    65 FRKLCIKTQTKWLT----IEDDSSSGDEDTN---DNSELESEKCAFSDFGKKKEGELVEETFQVL 122

  Fly   129 IMEEPLEDGVGETSQAYETSTVVDDLDEDDLLVPNSTDSDYQPIERCRKAKVRKTRMTKRGRGRP 193
            |.|||::                                  :.:.|..||::|:.
  Fly   123 IEEEPMD----------------------------------KTLNRDAKAQLRED---------- 143

  Fly   194 RGASSGHPRSFSEERPPVQASFKSSPEVSSTNIMCEICGNIYSKRAALNIHMRRHMAEKPFKCEI 258
                     ...|:..|.|...|.|.::.....:||:||...:.:.....|||:|..|:||.|:.
  Fly   144 ---------GIDEKCVPSQKIIKVSTKLDDQIYICELCGTHATSKPTFQRHMRKHRGERPFGCKD 199

  Fly   259 CSKSFAGPSELNRHIRVHTGEKPFLCKYCNRSFADRSSNIRHERTHTNERPFTCSTCGKAFSYSN 323
            |...|....||..|.||||||:||.|::|.:.:......:.|||||||:||:.|..|||.|:.:.
  Fly   200 CDARFLSAGELRAHHRVHTGEQPFACRFCEKRYVSYMGRLIHERTHTNDRPYVCEECGKKFTTAY 264

  Fly   324 VLKNHMLTHTGEKPFLCRVCNKTFSRKHQLDQHLGTMTHQQTVIHHKN 371
            ||||||:.||||:.|.|.:|:::|.||..|..|..:|.|.|.|...|:
  Fly   265 VLKNHMVIHTGERNFRCDICDRSFQRKAHLVTHTRSMMHLQNVKKQKS 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071	22/74 (30%)
		C2H2 Zn finger	228..248	CDD:275368	7/19 (37%)
		zf-H2C2_2	240..264	CDD:290200	9/23 (39%)
		COG5048	249..>362	CDD:227381	52/112 (46%)
		C2H2 Zn finger	256..276	CDD:275368	7/19 (37%)
		zf-H2C2_2	268..292	CDD:290200	13/23 (57%)
		C2H2 Zn finger	284..304	CDD:275368	5/19 (26%)
		zf-H2C2_2	299..321	CDD:290200	14/21 (67%)
		C2H2 Zn finger	312..332	CDD:275368	11/19 (58%)
		zf-H2C2_2	325..349	CDD:290200	13/23 (57%)
		C2H2 Zn finger	340..362	CDD:275368	8/21 (38%)
ouib	NP_649822.2	zf-AD	5..78	CDD:214871	22/76 (29%)
		COG5048	<158..300	CDD:227381	60/141 (43%)
		C2H2 Zn finger	169..189	CDD:275368	7/19 (37%)
		C2H2 Zn finger	197..217	CDD:275368	7/19 (37%)
		zf-H2C2_2	209..234	CDD:290200	13/24 (54%)
		C2H2 Zn finger	225..245	CDD:275368	5/19 (26%)
		zf-H2C2_2	241..262	CDD:290200	14/20 (70%)
		C2H2 Zn finger	253..273	CDD:275368	11/19 (58%)
		zf-H2C2_2	266..288	CDD:290200	12/21 (57%)
		C2H2 Zn finger	281..299	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960