DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14711 and CG14667

DIOPT Version :9

Sequence 1:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster

Alignment Length:	390	Identity:	93/390 - (23%)
Similarity:	162/390 - (41%)	Gaps:	89/390 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LCRICLTEDINSEAMAPLFDDNDAQCR-ELVRKIEEVGSIKLVPLQNIPSMLCYSCVERLTSAHK 69
            :||||..:.:..:....:|    ...| :.:.:::.:..::|...|.:|.::|..|...|..|.|
  Fly     6 VCRICANKIMGHQRDRNIF----IHMRGKYLGQLKLITGVELTRNQGLPEIVCERCFSELDLATK 66

  Fly    70 FRELCQESE--------RTFATNVVKAEMKSEPTDEVPHVVADNIEYIYESANDFI--DGVEDDI 124
            |||.|..|:        :|...:.|..|:.|||.|| ..:.||.:|..|:. :.::  .|.:::
  Fly    67 FRERCIFSQKYLLDIIKKTSDQSTVHVELSSEPLDE-QLIDADQLETHYDD-DQYVCYQGTKEE- 128

  Fly   125 GMENIMEEPLED----GVGETSQAYETSTVVDDLDEDDLLVPNSTDSDYQPIERCRKAKVRKTRM 185
             .:::.|..|:|    .|...::|...:...:||.|             |.:||..|.:
  Fly   129 -HQDLEEIELDDDPSAAVIAAAEAAAEAAQQEDLQE-------------QEMERAAKRR------ 173

  Fly   186 TKRGRGRPRGASSGHPRSFSEERPPVQASFKSSPEVSSTNIMCEICGN------IYSKRAALNIH 244
                                                 |...:|:.||.      :|::.  ||.|
  Fly   174 -------------------------------------SNFFICDECGTLFHDAFLYTEH--LNGH 199

  Fly   245 MRRHMAEKPFKCEICSKSFAGPSELNRH-IRVHTGEKPFLCKYCNRSFADRSSNIRHERTHTNER 308
            ..|....:.|.|..|.::|...:.|.:| .:||...:.|.|..|:.:||...:.:||::.|.|||
  Fly   200 QNRRDMNQFFPCPECPQTFNKKALLKQHRTQVHLINRRFQCTICHEAFASLGAKLRHDKAHKNER 264

  Fly   309 PFTCSTCGKAFSYSNVLKNHMLTHTGE-KPFLCRVCNKTFSRKHQLDQHLGTMTHQQTVIHHKNE 372
            |:.|..||..||..:.|:||..||:.: :.|.|..||..|..:..|..|..|..|::...:.::|
  Fly   265 PYPCLECGMIFSSVSELQNHFSTHSKQIRKFRCEPCNMDFITRRGLVAHTKTAPHKRLAKYMQDE 329

Fly 373 372
Fly 330 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071	19/83 (23%)
		C2H2 Zn finger	228..248	CDD:275368	7/25 (28%)
		zf-H2C2_2	240..264	CDD:290200	7/23 (30%)
		COG5048	249..>362	CDD:227381	38/114 (33%)
		C2H2 Zn finger	256..276	CDD:275368	5/20 (25%)
		zf-H2C2_2	268..292	CDD:290200	7/24 (29%)
		C2H2 Zn finger	284..304	CDD:275368	6/19 (32%)
		zf-H2C2_2	299..321	CDD:290200	11/21 (52%)
		C2H2 Zn finger	312..332	CDD:275368	8/19 (42%)
		zf-H2C2_2	325..349	CDD:290200	10/24 (42%)
		C2H2 Zn finger	340..362	CDD:275368	7/21 (33%)
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	19/77 (25%)
		C2H2 Zn finger	179..199	CDD:275368	6/21 (29%)
		C2H2 Zn finger	211..232	CDD:275368	5/20 (25%)
		C2H2 Zn finger	240..260	CDD:275368	6/19 (32%)
		zf-C2H2_8	243..313	CDD:292531	26/69 (38%)
		C2H2 Zn finger	268..288	CDD:275368	8/19 (42%)
		C2H2 Zn finger	297..316	CDD:275368	6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960