DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14711 and klf-3

DIOPT Version :9

Sequence 1:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_001022205.1	Gene:	klf-3 / 191713	WormBaseID:	WBGene00003480	Length:	315	Species:	Caenorhabditis elegans

Alignment Length:	355	Identity:	85/355 - (23%)
Similarity:	128/355 - (36%)	Gaps:	128/355 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 VVKAEMKSEPTDEVPHVVADNIEYIYESANDFIDGVEDDIGMENIMEEPLEDGVGETSQAYETST 149
            ::|.|..:.|..|             |...|..:.:|.|...:|:   |..:.: |...|:
Worm     1 MLKMEQSAPPRYE-------------EDWADVYEFIERDSSRKNV---PAIEAI-ERRLAF---- 44

  Fly   150 VVDDLDEDDLLVPNSTDSDYQPIERCRKAKVRKTRMTKRGRGRPRGASSGHPR---SFSEERPPV 211
                   ..|:.||.....:.||.             ..||..||......|.   .||...|||
Worm    45 -------SPLITPNPGAKQFAPIH-------------VPGREPPRMLLPPTPHFQAPFSPHPPPV 89

  Fly   212 Q-----------ASFKSSPEV-SSTNIMCEICGNIY-----SKR-----------AALNIHMR-- 246
            |           .|:::.||| ...:|:|    |.|     |.|           :|:.:|..
Worm    90 QQVPSYSPPHAPPSYETYPEVYYPPHIIC----NPYDVPTTSDRNPPYYTEVTTVSAVTLHSMTP 150

  Fly   247 -RHMAEKP-----------------FKCEI------------------CSKSFAGPSELNRHIRV 275
             .|..|.|                 .|.||                  .|.:.:..|.|.|..|:
Worm   151 PTHKIETPPSSPENSFGPLASQLPAIKMEIPMHPLPHNGELDSTRSSPSSTTSSERSPLQRKSRI 215

  Fly   276 HTG-----EKPFL---CKY--CNRSFADRSSNIR-HERTHTNERPFTC--STCGKAFSYSNVLKN 327
            .:.     :|.|:   |.|  |.:.:: :||::: |||||:.|:||.|  ..|...|:.|:.|..
Worm   216 ESNKRNPTDKKFVVHACTYPGCFKKYS-KSSHLKAHERTHSGEKPFVCKWQNCSWKFARSDELTR 279

  Fly   328 HMLTHTGEKPFLCRVCNKTFSRKHQLDQHL 357
            ||..|||:|||.|.:|::.|:|...|..|:
Worm   280 HMRKHTGDKPFRCSLCDRNFARSDHLSLHM 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071
		C2H2 Zn finger	228..248	CDD:275368	7/38 (18%)
		zf-H2C2_2	240..264	CDD:290200	9/61 (15%)
		COG5048	249..>362	CDD:227381	44/157 (28%)
		C2H2 Zn finger	256..276	CDD:275368	7/37 (19%)
		zf-H2C2_2	268..292	CDD:290200	8/33 (24%)
		C2H2 Zn finger	284..304	CDD:275368	8/22 (36%)
		zf-H2C2_2	299..321	CDD:290200	11/24 (46%)
		C2H2 Zn finger	312..332	CDD:275368	7/21 (33%)
		zf-H2C2_2	325..349	CDD:290200	12/23 (52%)
		C2H2 Zn finger	340..362	CDD:275368	6/18 (33%)
klf-3	NP_001022205.1	C2H2 Zn finger	235..254	CDD:275368	6/19 (32%)
		C2H2 Zn finger	262..284	CDD:275368	7/21 (33%)
		zf-H2C2_2	276..301	CDD:290200	12/24 (50%)
		C2H2 Zn finger	292..312	CDD:275368	6/18 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000