DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG14711 and ZNF846

DIOPT Version :9

Sequence 1:NP_650094.1 Gene:CG14711 / 41395 FlyBaseID:FBgn0037922 Length:377 Species:Drosophila melanogaster
Sequence 2:NP_001071092.1 Gene:ZNF846 / 162993 HGNCID:27260 Length:533 Species:Homo sapiens


Alignment Length:379 Identity:105/379 - (27%)
Similarity:163/379 - (43%) Gaps:90/379 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 CVERLTSAHKFREL--------------CQESERTFAT-NVVKAEMKSEPTDEVPHVVADNIEYI 109
            ||:...:.::|..|              |::..|||.. :.:|..::|...|:  |.|.......
Human   172 CVKHEKAFNQFPNLTRQNKTHTQEKLCECKDCWRTFLNQSSLKLHIRSHNGDK--HYVCKECGKA 234

  Fly   110 YESANDFIDGVEDDIGMENIMEEPLEDGVGETSQAYETSTVVDDLDEDDLLVPNSTDSDYQP--I 172
            :.:::..|..     |..:..|:|..  ..|..:|:..||        .|.:...|.|..:|  .
Human   235 FSNSSHLIGH-----GRIHSGEKPYV--CKECGKAFTQST--------GLKLHIRTHSGEKPYKC 284

  Fly   173 ERCRKAKVRKTRMTKRGR-------------GRPRGASSG---HPRSFSEERPPV-----QASFK 216
            :.|.||....:.:|...|             |:....|:|   |.|..:.|:|..     :|...
Human   285 KECGKAFTHSSYLTDHTRIHSGKKPYVCMECGKAFTRSTGLILHMRIHTGEKPYECKECGKAFIH 349

  Fly   217 SSPEVSSTNI-------MCEICGNIYSKRAALNIHMRRHMAEKPFKCEICSKSFAGPSELNRHIR 274
            ||.......|       :|:.||..:::.:.|.:|||.|..|||::|:.|.|:|...|.|::|:|
Human   350 SSYLTKHVRIHSGEKLYLCKACGKAFTRSSGLVLHMRTHTGEKPYECKECGKAFNNSSMLSQHVR 414

  Fly   275 VHTGEKPFLCKYCNRSFAD---------------------------RSSNIR-HERTHTNERPFT 311
            :||||||:.||.|.::|..                           ||:|:. |.||||.|:|:.
Human   415 IHTGEKPYECKECGKAFTQSSGLSTHLRTHTGEKACECKECGKAFARSTNLNMHMRTHTGEKPYA 479

  Fly   312 CSTCGKAFSYSNVLKNHMLTHTGEKPFLCRVCNKTFSRKHQLDQHLGTMTHQQT 365
            |..|||||.||..|..|..||||.||:.|:.|.|.|::...|.:||.|...::|
Human   480 CKECGKAFRYSTYLNVHTRTHTGAKPYECKKCGKNFTQSSALAKHLRTKACEKT 533

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14711NP_650094.1 zf-AD 6..81 CDD:285071 6/34 (18%)
C2H2 Zn finger 228..248 CDD:275368 7/19 (37%)
zf-H2C2_2 240..264 CDD:290200 11/23 (48%)
COG5048 249..>362 CDD:227381 55/140 (39%)
C2H2 Zn finger 256..276 CDD:275368 8/19 (42%)
zf-H2C2_2 268..292 CDD:290200 12/23 (52%)
C2H2 Zn finger 284..304 CDD:275368 9/47 (19%)
zf-H2C2_2 299..321 CDD:290200 13/22 (59%)
C2H2 Zn finger 312..332 CDD:275368 10/19 (53%)
zf-H2C2_2 325..349 CDD:290200 12/23 (52%)
C2H2 Zn finger 340..362 CDD:275368 8/21 (38%)
ZNF846NP_001071092.1 KRAB 8..67 CDD:214630
KRAB 8..45 CDD:279668
COG5048 106..496 CDD:227381 89/340 (26%)
C2H2 Zn finger 120..136 CDD:275368
C2H2 Zn finger 200..220 CDD:275368 5/19 (26%)
C2H2 Zn finger 228..248 CDD:275368 2/24 (8%)
C2H2 Zn finger 256..276 CDD:275368 5/27 (19%)
zf-H2C2_2 269..293 CDD:290200 7/23 (30%)
C2H2 Zn finger 284..304 CDD:275368 5/19 (26%)
zf-H2C2_2 296..321 CDD:290200 3/24 (13%)
C2H2 Zn finger 312..332 CDD:275368 5/19 (26%)
zf-H2C2_2 328..347 CDD:290200 4/18 (22%)
zf-C2H2 338..360 CDD:278523 3/21 (14%)
C2H2 Zn finger 340..360 CDD:275368 3/19 (16%)
zf-H2C2_2 352..377 CDD:290200 4/24 (17%)
C2H2 Zn finger 368..388 CDD:275368 7/19 (37%)
zf-H2C2_2 381..405 CDD:290200 12/23 (52%)
C2H2 Zn finger 396..416 CDD:275368 8/19 (42%)
zf-H2C2_2 408..433 CDD:290200 13/24 (54%)
C2H2 Zn finger 424..444 CDD:275368 4/19 (21%)
zf-H2C2_2 437..461 CDD:290200 0/23 (0%)
C2H2 Zn finger 452..472 CDD:275368 5/19 (26%)
zf-H2C2_2 464..489 CDD:290200 14/24 (58%)
C2H2 Zn finger 480..500 CDD:275368 10/19 (53%)
zf-H2C2_2 492..517 CDD:290200 12/24 (50%)
C2H2 Zn finger 508..527 CDD:275368 7/18 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.