DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14711 and ZNF582

DIOPT Version :9

Sequence 1:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_001307300.2	Gene:	ZNF582 / 147948	HGNCID:	26421	Length:	517	Species:	Homo sapiens

Alignment Length:	211	Identity:	71/211 - (33%)
Similarity:	103/211 - (48%)	Gaps:	43/211 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 CRKAKVRKTRMTKRGRGRPRGASSGHPRSFSEERPPVQASFKSSPEVSSTNIMCEICGNIYSKRA 239
            |.||..|.:::.:            |.|:.:.|:|                ..|:.||..:::.:
Human   260 CEKAFSRSSQLIE------------HQRTHTGEKP----------------YQCKECGKAFNRIS 296

  Fly   240 ALNIHMRRHMAEKPFKCEICSKSFAGPSELNRHIRVHTGEKPFLCKYCNRSFADRSSNIRHERTH 304
            .|.:|.|.|..|||:.|:.|.|:|:..|:|.:|..||||.|.:.||.|.::|...|:.|||:|.|
Human   297 HLKVHYRIHTGEKPYACKECGKTFSHRSQLIQHQTVHTGRKLYECKECGKAFNQGSTLIRHQRIH 361

  Fly   305 TNERPFTCSTCGKAFSYSNVLKNHMLTHTGEKPFLCRVCNKTFSRKHQLDQHLGTMT-------- 361
            |.|:|:.|..|||||..|:.||.|...||||||:.|:||.:.|.|...|..|....|
Human   362 TGEKPYECKVCGKAFRVSSQLKQHQRIHTGEKPYQCKVCGRAFKRVSHLTVHYRIHTGEKPYECK 426

  Fly   362 -------HQQTVIHHK 370
                   |...:|||:
Human   427 ECGKAFSHCSQLIHHQ 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071
		C2H2 Zn finger	228..248	CDD:275368	6/19 (32%)
		zf-H2C2_2	240..264	CDD:290200	10/23 (43%)
		COG5048	249..>362	CDD:227381	52/127 (41%)
		C2H2 Zn finger	256..276	CDD:275368	7/19 (37%)
		zf-H2C2_2	268..292	CDD:290200	10/23 (43%)
		C2H2 Zn finger	284..304	CDD:275368	9/19 (47%)
		zf-H2C2_2	299..321	CDD:290200	13/21 (62%)
		C2H2 Zn finger	312..332	CDD:275368	10/19 (53%)
		zf-H2C2_2	325..349	CDD:290200	13/23 (57%)
		C2H2 Zn finger	340..362	CDD:275368	8/36 (22%)
ZNF582	NP_001307300.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910