DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14711 and si:ch73-109d9.3

DIOPT Version :9

Sequence 1:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	XP_005160142.1	Gene:	si:ch73-109d9.3 / 101883524	ZFINID:	ZDB-GENE-141212-331	Length:	470	Species:	Danio rerio

Alignment Length:	172	Identity:	53/172 - (30%)
Similarity:	73/172 - (42%)	Gaps:	26/172 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 PNSTDSDYQPIERCRKAKVRKTRMTKRGRGRPRGASSGHPRSFSEERPPVQASFKSSPEVSSTNI 226
            ||:..||:..::..|.....|....   |..|.||..   |||:...|.     :|.|.|.:..:
Zfish   318 PNAAMSDHGAVDLNRSLPAPKLSQV---RQYPEGAGE---RSFNTMNPG-----RSLPPVVNMRV 371

  Fly   227 MCEICGNIYSKRAALNIHMRRHMAEKPFKCEICSKSFAGPSELNRHIRVHTGEKPFLCKYCNRSF 291
            ..:          |.||     .|:....|..|.|.|:....|..|.::|||::.|.|..|.|||
Zfish   372 QVD----------ARNI-----SAKTTHNCSQCGKGFSHLCHLRAHQQIHTGDRQFCCTICGRSF 421

  Fly   292 ADRSSNIRHERTHTNERPFTCSTCGKAFSYSNVLKNHMLTHT 333
            ...|:...|.|.||.|||:.|:.|||.|:....||.|...|:
Zfish   422 TKLSNLKAHRRVHTGERPYICADCGKRFTQKCNLKRHQRIHS 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071
		C2H2 Zn finger	228..248	CDD:275368	3/19 (16%)
		zf-H2C2_2	240..264	CDD:290200	7/23 (30%)
		COG5048	249..>362	CDD:227381	33/85 (39%)
		C2H2 Zn finger	256..276	CDD:275368	6/19 (32%)
		zf-H2C2_2	268..292	CDD:290200	10/23 (43%)
		C2H2 Zn finger	284..304	CDD:275368	8/19 (42%)
		zf-H2C2_2	299..321	CDD:290200	12/21 (57%)
		C2H2 Zn finger	312..332	CDD:275368	8/19 (42%)
		zf-H2C2_2	325..349	CDD:290200	4/9 (44%)
		C2H2 Zn finger	340..362	CDD:275368
si:ch73-109d9.3	XP_005160142.1	RPW8	<21..>72	CDD:283345
		zf-C2H2	384..406	CDD:278523	6/21 (29%)
		C2H2 Zn finger	386..406	CDD:275368	6/19 (32%)
		zf-H2C2_2	398..422	CDD:290200	10/23 (43%)
		C2H2 Zn finger	414..434	CDD:275368	8/19 (42%)
		zf-H2C2_2	426..451	CDD:290200	12/24 (50%)
		C2H2 Zn finger	442..462	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581386
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930