DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14711 and si:ch211-155e24.3

DIOPT Version :9

Sequence 1:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_001121882.2	Gene:	si:ch211-155e24.3 / 100150696	ZFINID:	ZDB-GENE-070912-116	Length:	340	Species:	Danio rerio

Alignment Length:	329	Identity:	81/329 - (24%)
Similarity:	125/329 - (37%)	Gaps:	61/329 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ELVRKIEEVGSIKLVPLQNIPSMLCYSCVERLTSAHKFRE----LCQESERTFATNVVKAEMKSE 93
            ||.|...::.|:|            ..||.......:.|.    :|..|:|..|......:.:..
Zfish    39 ELSRSRRDIESLK------------RKCVLMDGELRRVRRRRVWICGTSDRFSAPLKNNRDQEQT 91

  Fly    94 PTDEVPHVVADNIEYIYESANDFIDGVEDDIGMENIMEEPLEDGVGETSQAYETSTVVDDLDEDD 158
            |...:             |....:..:|::|....|.:|....|. |.....|.:|.:.:.|...
Zfish    92 PDQTL-------------SIQQSVCSLENEIRAPEIKQEQEPSGT-EQQIPTEHNTEIPNADFGA 142

  Fly   159 LLVPNS----TDSDYQPI-------ERCRKAKVRKTRMTKRGRGRPRGASSGHPRSFSEERPPVQ 212
            |.:.|:    |.:..:||       |.|.:.:|      |......:..:..||.....|..|.:
Zfish   143 LEIQNTLFAHTQTSTEPIKQDEEEEEECVELQV------KAEEENHQHWTFEHPIDVQLENTPAE 201

  Fly   213 ASFKSSPEV---SSTNIMCE----------ICGNIYSKRAALNIHMRRHMAEKPFKCEICSKSFA 264
            ...:...:.   |..:...|          :||...|.| .|..|....:..|.:.|..|.|:|:
Zfish   202 QPLQHEEDTHAQSDDHTQMEFNAGERDEASMCGVSASVR-RLRTHWHSSVEVKRYSCTFCRKNFS 265

  Fly   265 GPSELNRHIRVHTGEKPFLCKYCNRSFADRSSNIRHERTHTNERPFTCSTCGKAFSYSNVLKNHM 329
            ..|:|..|:|.|||||||.|..|.|||....:.|||...|:.|:|:.|:.|||.|:..:.||:|.
Zfish   266 RFSQLKEHLRSHTGEKPFSCAQCGRSFTKHCNLIRHAVVHSGEKPYQCAQCGKRFTQRSSLKSHQ 330

  Fly   330 LTHT 333
            ..||
Zfish   331 RMHT 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071	11/51 (22%)
		C2H2 Zn finger	228..248	CDD:275368	7/29 (24%)
		zf-H2C2_2	240..264	CDD:290200	6/23 (26%)
		COG5048	249..>362	CDD:227381	37/85 (44%)
		C2H2 Zn finger	256..276	CDD:275368	8/19 (42%)
		zf-H2C2_2	268..292	CDD:290200	14/23 (61%)
		C2H2 Zn finger	284..304	CDD:275368	8/19 (42%)
		zf-H2C2_2	299..321	CDD:290200	10/21 (48%)
		C2H2 Zn finger	312..332	CDD:275368	8/19 (42%)
		zf-H2C2_2	325..349	CDD:290200	5/9 (56%)
		C2H2 Zn finger	340..362	CDD:275368
si:ch211-155e24.3	NP_001121882.2	C2H2 Zn finger	257..277	CDD:275368	8/19 (42%)
		zf-H2C2_2	270..294	CDD:316026	15/23 (65%)
		C2H2 Zn finger	285..305	CDD:275368	8/19 (42%)
		zf-H2C2_2	297..322	CDD:316026	11/24 (46%)
		zf-C2H2	311..333	CDD:306579	8/21 (38%)
		C2H2 Zn finger	313..333	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581384
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930