Protein Alignment Zaf1 and ZNF611

DIOPT Version :10

• Sequence 1: NP_731602.1
• Gene: Zaf1 / 41394
• FlyBaseID: FBgn0037921
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_112234.3
• Gene: ZNF611 / 81856
• HGNCID: 28766
• Length: 705
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 101/374 - (27%)
• Similarity: 152/374 - (40%)
• Gaps: 61/374 - (16%)

  Fly    15 KKGTQSTLQSLFESNAHKLLISYAGTSVKPDDGLPDQICTVCLMQLEEVDRFLSACKQSDAHLRS 79
            ||.|.||     :.:.|:    :||.  ||   :.||:.:.....|.|:..|     |....:.:
Human   133 KKLTGST-----DQHDHR----HAGN--KP---IKDQLGSSFYSHLPELHIF-----QIKGEIGN 178

  Fly    80 LVRQTLSSASAFETLEDKDQLEQKKRARKQNISGRLIEENPINFKTQENALETTKDDEILPINKF 144
            .:.::.:.|.:..|.       |:...|.|.........||:|........|....::....||.
Human   179 QLEKSTNDAPSVSTF-------QRISCRPQTQISNNYGNNPLNSSLLPQKQEVHMREKSFQCNKS 236

  Fly   145 SSDF----------------------VFDLNVNAENEKDIHQEDYTISDMDLDREISDQNYSETY 187
            ...|                      |.....|.|.....|...:|:     ::....:...:|:
Human   237 GKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHEQYLACHDRCHTV-----EKPYKCKECGKTF 296

  Fly   188 SQESSAATDSIQETSEDYHNLE-------PSADYVIDLGVACEPDKYRCKICSNTYRCLSQLNAH 245
            |||||........|....:|..       .::..:||..:....:.|:|..|...:...||| :|
Human   297 SQESSLTCHRRLHTGVKRYNCNECGKIFGQNSALLIDKAIDTGENPYKCNECDKAFNQQSQL-SH 360

  Fly   246 SQVHRKEKDHQCEVCQKTFRAACNLKTHMRTHTGEKPYQCCYCSRRFADNSTHRKHERLHTNERP 310
            .::|..||.::||.|.|.|.....::||.|.|||||||:|..|...|..:|...:|.|:||.::.
Human   361 HRIHTGEKPYKCEECDKVFSRKSTIETHKRIHTGEKPYRCKVCDTAFTWHSQLARHRRIHTAKKT 425

  Fly   311 YACNICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEFRLKHQLTAHEK 359
            |.||.||||||..||...|:.||..|||:||.:|.|.|....||..|.:
Human   426 YKCNECGKTFSHKSSLVCHHRLHGGEKSYKCKVCDKAFVWSSQLAKHTR 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zaf1	NP_731602.1	zf-AD	9..79	CDD:214871	16/63 (25%)
		SFP1	<161..320	CDD:227516	51/165 (31%)
		C2H2 Zn finger	229..249	CDD:275368	6/19 (32%)
		C2H2 Zn finger	257..277	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..293	CDD:463886	12/23 (52%)
		C2H2 Zn finger	285..305	CDD:275368	6/19 (32%)
		C2H2 Zn finger	313..333	CDD:275368	11/19 (58%)
		C2H2 Zn finger	341..359	CDD:275368	7/17 (41%)
ZNF611	NP_112234.3	KRAB	24..60	CDD:460171
		C2H2 Zn finger	233..253	CDD:275368	3/19 (16%)
		COG5048	256..698	CDD:227381	73/225 (32%)
		C2H2 Zn finger	261..281	CDD:275368	4/19 (21%)
		C2H2 Zn finger	289..309	CDD:275368	6/19 (32%)
		C2H2 Zn finger	345..364	CDD:275368	6/19 (32%)
		C2H2 Zn finger	372..392	CDD:275368	8/19 (42%)
		C2H2 Zn finger	400..420	CDD:275368	6/19 (32%)
		C2H2 Zn finger	428..448	CDD:275368	11/19 (58%)
		C2H2 Zn finger	456..475	CDD:275368	7/19 (37%)
		C2H2 Zn finger	484..504	CDD:275368
		C2H2 Zn finger	512..532	CDD:275368
		C2H2 Zn finger	540..560	CDD:275368
		C2H2 Zn finger	568..588	CDD:275368
		C2H2 Zn finger	596..616	CDD:275368
		C2H2 Zn finger	624..644	CDD:275368
		C2H2 Zn finger	652..672	CDD:275368
		C2H2 Zn finger	680..700	CDD:275368