DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6808 and Zfp24

DIOPT Version :9

Sequence 1:	NP_001247055.1	Gene:	CG6808 / 41394	FlyBaseID:	FBgn0037921	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_001344376.1	Gene:	Zfp24 / 59057	MGIID:	1929704	Length:	368	Species:	Mus musculus

Alignment Length:	322	Identity:	82/322 - (25%)
Similarity:	142/322 - (44%)	Gaps:	67/322 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VKPDDGLPDQICTVCLMQLEEVDRFLSACKQSDAHLRSLVRQ--TLSSASAFETLED-KDQLEQ- 102
            ::|:....:||     ::|..:::|::...:   .|::.||:  ..:...|...||| :.:|:.
Mouse    81 LRPETHTKEQI-----LELVVLEQFVAILPK---ELQTWVREHHPENGEEAVAVLEDLESELDDP 137

  Fly   103 ----KKRARKQNISGRLIEENPINFKTQENALETTKDDEILPINKFSSDFVFDLNVNAENEK--- 160
                ..|.:|:.:   |:||           :.:.:|.:.||.::..:         .||:.
Mouse   138 GQPVSLRRQKREV---LVEE-----------ITSQEDAQGLPSSELDA---------VENQLKWA 179

  Fly   161 --DIHQEDYTISDMDLDREISDQNYSETYSQESSAATDSIQETSEDYHNLEPSADYVIDLGVAC- 222
              ::|      |....|.:.:.:|.:....||.::|    .|:.|....|......:...|..|
Mouse   180 SWELH------SLRHCDDDATTENGALAPKQEMASA----GESHEGPGTLNIGVPQLFKYGETCF 234

  Fly   223 ---------EPDKYRCKICSNTYRCLSQLNA---HSQVHRKEKDHQCEVCQKTFRAACNLKTHMR 275
                     .|.:.:..||....:..||.:|   |.::|..||.:.|..|.|.|..:..|..|.|
Mouse   235 PKGRFERKRNPSRKKQHICDECGKHFSQGSALILHQRIHSGEKPYGCVECGKAFSRSSILVQHQR 299

  Fly   276 THTGEKPYQCCYCSRRFADNSTHRKHERLHTNERPYACNICGKTFSLSSSRNAHYYLHSSEK 337
            .|||||||:|..|.:.|:.||....|:|:||.|:||.|..|||::|.||:...|...|::||
Mouse   300 VHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQCGKSYSQSSNLFRHQRRHNAEK 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6808	NP_001247055.1	zf-AD	9..79	CDD:214871	6/36 (17%)
		C2H2 Zn finger	229..249	CDD:275368	6/22 (27%)
		zf-C2H2	255..277	CDD:278523	7/21 (33%)
		C2H2 Zn finger	257..277	CDD:275368	7/19 (37%)
		zf-H2C2_2	269..293	CDD:290200	12/23 (52%)
		C2H2 Zn finger	285..305	CDD:275368	7/19 (37%)
		zf-H2C2_2	299..321	CDD:290200	11/21 (52%)
		C2H2 Zn finger	313..333	CDD:275368	8/19 (42%)
		C2H2 Zn finger	341..359	CDD:275368
Zfp24	NP_001344376.1	SCAN	48..159	CDD:128708	18/99 (18%)
		COG5048	<249..329	CDD:227381	30/79 (38%)
		Necessary and sufficient for nuclear localization. /evidence=ECO:0000250	251..301		16/49 (33%)
		C2H2 Zn finger	253..273	CDD:275368	5/19 (26%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		COG5048	305..>358	CDD:227381	23/52 (44%)
		C2H2 Zn finger	309..329	CDD:275368	7/19 (37%)
		C2H2 Zn finger	337..357	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000