DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6808 and ZNF77

DIOPT Version :9

Sequence 1:NP_001247055.1 Gene:CG6808 / 41394 FlyBaseID:FBgn0037921 Length:375 Species:Drosophila melanogaster
Sequence 2:NP_067040.1 Gene:ZNF77 / 58492 HGNCID:13150 Length:545 Species:Homo sapiens


Alignment Length:309 Identity:84/309 - (27%)
Similarity:118/309 - (38%) Gaps:69/309 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    91 FETLEDKDQLEQKKRARKQNISGRLIEENP-----------------INFKTQENALETTKDDEI 138
            |:...|:.|:.| :..|.|  .|||.|.|.                 .::.|:....|.||..:.
Human    89 FDNTGDQHQIPQ-RHLRSQ--LGRLCESNEGHQCGETLSQTANLLVHKSYPTEAKPSECTKCGKA 150

  Fly   139 LPINKFSSDFVFDLNVNAENEKDIHQEDYTISDMDLDREISDQNYSETYSQESSAATDSIQETSE 203
            .                 ||.:..|.......:       ..|..|....|.....|.::::...
Human   151 F-----------------ENRQRSHTGQRPCKE-------CGQACSCLSCQSPPMKTQTVEKPCN 191

  Fly   204 DYHNLEPSADYVIDL----GVACE--------PDKYR-------------CKICSNTYRCLSQLN 243
            ...:...|..||..|    ...|:        |..:|             ||:|..|:...|.|.
Human   192 CQDSRTASVTYVKSLSSKKSYECQKCGKAFICPSSFRGHVNSHHGQKTHACKVCGKTFMYYSYLT 256

  Fly   244 AHSQVHRKEKDHQCEVCQKTFRAACNLKTHMRTHTGEKPYQCCYCSRRFADNSTHRKHERLHTNE 308
            .|.:.|..||.::|:.|.|.|......:.|:|||||||||:|.:|.:.|:..|:.|.|.|.||.|
Human   257 RHVRTHTGEKPYECKECGKAFSCPSYFREHVRTHTGEKPYECKHCGKSFSCYSSFRDHVRTHTGE 321

  Fly   309 RPYACNICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEFRLKHQLTAH 357
            :|..|..|||.|:..||...|...||.||.::|..|.|.||....|.||
Human   322 KPCQCKHCGKAFTCYSSLREHGRTHSGEKPYECKECGKAFRYPSSLRAH 370

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6808NP_001247055.1 zf-AD 9..79 CDD:214871
C2H2 Zn finger 229..249 CDD:275368 7/19 (37%)
zf-C2H2 255..277 CDD:278523 6/21 (29%)
C2H2 Zn finger 257..277 CDD:275368 6/19 (32%)
zf-H2C2_2 269..293 CDD:290200 12/23 (52%)
C2H2 Zn finger 285..305 CDD:275368 7/19 (37%)
zf-H2C2_2 299..321 CDD:290200 11/21 (52%)
C2H2 Zn finger 313..333 CDD:275368 8/19 (42%)
C2H2 Zn finger 341..359 CDD:275368 8/17 (47%)
ZNF77NP_067040.1 KRAB 4..44 CDD:307490
C2H2 Zn finger 164..184 CDD:275368 3/26 (12%)
C2H2 Zn finger 214..234 CDD:275368 3/19 (16%)
COG5048 237..>544 CDD:227381 55/134 (41%)
C2H2 Zn finger 242..262 CDD:275368 7/19 (37%)
C2H2 Zn finger 270..290 CDD:275368 6/19 (32%)
C2H2 Zn finger 298..318 CDD:275368 7/19 (37%)
C2H2 Zn finger 326..346 CDD:275368 8/19 (42%)
C2H2 Zn finger 354..374 CDD:275368 8/17 (47%)
C2H2 Zn finger 382..402 CDD:275368
C2H2 Zn finger 410..430 CDD:275368
C2H2 Zn finger 438..458 CDD:275368
C2H2 Zn finger 466..486 CDD:275368
C2H2 Zn finger 494..514 CDD:275368
C2H2 Zn finger 522..542 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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