DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6808 and znf1015

DIOPT Version :9

Sequence 1:	NP_001247055.1	Gene:	CG6808 / 41394	FlyBaseID:	FBgn0037921	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_001025341.1	Gene:	znf1015 / 562615	ZFINID:	ZDB-GENE-050913-139	Length:	436	Species:	Danio rerio

Alignment Length:	134	Identity:	50/134 - (37%)
Similarity:	73/134 - (54%)	Gaps:	5/134 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 CKICSNTYRCLSQLNAHSQVHRKEKDHQCEVCQKTFRAACNLKTHMRTHTGEKPYQCCYCSRRFA 293
            |:.|..::.|.:....|.:||..||.:.|..|.|:|....||.:|||.||||||:.|.||.:||:
Zfish   275 CEQCGRSFFCEATYEKHMRVHTGEKPYSCTECGKSFSQKENLTSHMRIHTGEKPFACEYCEKRFS 339

  Fly   294 DNSTHRKHERLHTNERPYACNICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEF-----RLKHQ 353
            .....:.|.|:||.|:||.|..|||.|:..:....|...|:.|:.:.|:.|.|.|     :::|.
Zfish   340 QLPALKVHMRVHTGEKPYTCAQCGKGFAQKNGLKIHMRTHTGERPYTCMQCGKNFISKETQIRHM 404

  Fly   354 LTAH 357
            .|.|
Zfish   405 KTHH 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6808	NP_001247055.1	zf-AD	9..79	CDD:214871
		C2H2 Zn finger	229..249	CDD:275368	4/19 (21%)
		zf-C2H2	255..277	CDD:278523	9/21 (43%)
		C2H2 Zn finger	257..277	CDD:275368	9/19 (47%)
		zf-H2C2_2	269..293	CDD:290200	15/23 (65%)
		C2H2 Zn finger	285..305	CDD:275368	7/19 (37%)
		zf-H2C2_2	299..321	CDD:290200	11/21 (52%)
		C2H2 Zn finger	313..333	CDD:275368	6/19 (32%)
		C2H2 Zn finger	341..359	CDD:275368	7/22 (32%)
znf1015	NP_001025341.1	COG5048	73..409	CDD:227381	50/134 (37%)
		C2H2 Zn finger	80..100	CDD:275368
		C2H2 Zn finger	108..128	CDD:275368
		C2H2 Zn finger	136..156	CDD:275368
		zf-H2C2_2	149..173	CDD:290200
		C2H2 Zn finger	164..184	CDD:275368
		zf-H2C2_2	176..200	CDD:290200
		C2H2 Zn finger	192..212	CDD:275368
		C2H2 Zn finger	220..240	CDD:275368
		C2H2 Zn finger	275..295	CDD:275368	4/19 (21%)
		zf-H2C2_2	289..312	CDD:290200	9/22 (41%)
		C2H2 Zn finger	303..323	CDD:275368	9/19 (47%)
		zf-H2C2_2	315..340	CDD:290200	16/24 (67%)
		C2H2 Zn finger	331..351	CDD:275368	7/19 (37%)
		zf-H2C2_2	343..368	CDD:290200	12/24 (50%)
		C2H2 Zn finger	359..379	CDD:275368	6/19 (32%)
		zf-H2C2_2	372..396	CDD:290200	7/23 (30%)
		C2H2 Zn finger	387..407	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910