DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6808 and ZNF691

DIOPT Version :9

Sequence 1:	NP_001247055.1	Gene:	CG6808 / 41394	FlyBaseID:	FBgn0037921	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_001229668.1	Gene:	ZNF691 / 51058	HGNCID:	28028	Length:	315	Species:	Homo sapiens

Alignment Length:	183	Identity:	59/183 - (32%)
Similarity:	92/183 - (50%)	Gaps:	7/183 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 ETYSQESSAATDSIQETSEDYH-------NLEPSADYVIDLGVACEPDKYRCKICSNTYRCLSQL 242
            :|::..|:..|.....|.|..:       :...|::.:....:..|...|:|..|..::|..|.|
Human   122 KTFNNTSNLRTHQRIHTGEKPYKCSECGKSFSRSSNRIRHERIHLEEKHYKCPKCQESFRRRSDL 186

  Fly   243 NAHSQVHRKEKDHQCEVCQKTFRAACNLKTHMRTHTGEKPYQCCYCSRRFADNSTHRKHERLHTN 307
            ..|.|.|..::.::|::|.|:|..:..|..|.|||....||.||.|.:.|:::|:...|.|.||.
Human   187 TTHQQDHLGKRPYRCDICGKSFSQSATLAVHHRTHLEPAPYICCECGKSFSNSSSFGVHHRTHTG 251

  Fly   308 ERPYACNICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEFRLKHQLTAHEKS 360
            ||||.|..||:|||..|:..||...|..||.::|.:|.|.|.....|..|:|:
Human   252 ERPYECTECGRTFSDISNFGAHQRTHRGEKPYRCTVCGKHFSRSSNLIRHQKT 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6808	NP_001247055.1	zf-AD	9..79	CDD:214871
		C2H2 Zn finger	229..249	CDD:275368	7/19 (37%)
		zf-C2H2	255..277	CDD:278523	7/21 (33%)
		C2H2 Zn finger	257..277	CDD:275368	7/19 (37%)
		zf-H2C2_2	269..293	CDD:290200	10/23 (43%)
		C2H2 Zn finger	285..305	CDD:275368	7/19 (37%)
		zf-H2C2_2	299..321	CDD:290200	12/21 (57%)
		C2H2 Zn finger	313..333	CDD:275368	9/19 (47%)
		C2H2 Zn finger	341..359	CDD:275368	6/17 (35%)
ZNF691	NP_001229668.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..90
		COG5048	<108..266	CDD:227381	45/143 (31%)
		C2H2 Zn finger	117..137	CDD:275368	3/14 (21%)
		C2H2 Zn finger	145..165	CDD:275368	1/19 (5%)
		C2H2 Zn finger	173..193	CDD:275368	7/19 (37%)
		C2H2 Zn finger	201..221	CDD:275368	7/19 (37%)
		C2H2 Zn finger	229..249	CDD:275368	7/19 (37%)
		C2H2 Zn finger	257..277	CDD:275368	9/19 (47%)
		zf-C2H2	283..305	CDD:306579	7/22 (32%)
		C2H2 Zn finger	285..305	CDD:275368	7/20 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3304
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950