Protein Alignment Zaf1 and ZNF716

DIOPT Version :10

• Sequence 1: NP_731602.1
• Gene: Zaf1 / 41394
• FlyBaseID: FBgn0037921
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_001152751.1
• Gene: ZNF716 / 441234
• HGNCID: 32458
• Length: 495
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 82/310 - (26%)
• Similarity: 131/310 - (42%)
• Gaps: 55/310 - (17%)

  Fly   100 LEQKKRARKQNIS-GRLIEENPINFK--TQENALETTKDDEI--LPINKFSSDFVFDLNV----N 155
            |||.|  ..|||. ..::.::|:...  ||:...|....|.:  :.:.::......||.|    .
Human    68 LEQNK--EPQNIKRNEMVAKHPVTCSHFTQDLQSEQGIKDSLQKVILRRYGKCGQEDLQVKKCCK 130

  Fly   156 AENEKDIHQEDYTISDMDLDREISDQNYS-------ETYSQESSAATDSIQETSEDYHNLEPSAD 213
            :..|.::|:..|...:..|.   :.||.:       :.:.:.|::.....:.|.:.:...:....
Human   131 SVGECEVHKGGYNYVNQCLS---ATQNKTFQTHKCVKVFGKFSNSNRHKTRHTGKKHFKCKNDGK 192

  Fly   214 YVIDLG-------VACEPDKYRCKICSNTYRCLSQLNAHSQVHRKEKDHQCEVCQKTFRAACNLK 271
            ....|.       :......|:|:.|..::.|.|.|..|.::|..||.::||.|.|.|..:.:|.
Human   193 SFCMLSRLNQHQIIHTREKSYKCEECGKSFNCSSTLTRHKRIHTGEKPYRCEECGKAFSWSASLT 257

  Fly   272 THMRTHTGEKPYQC--------------------------C-YCSRRFADNSTHRKHERLHTNER 309
            .|.|.|||||||.|                          | .|.:.|:.:||...|:|:||.||
Human   258 KHKRIHTGEKPYTCEERGKVFSRSTLTNYKRIHTGEKPYTCEECGKAFSRSSTLTNHKRIHTGER 322

  Fly   310 PYACNICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEFRLKHQLTAHEK 359
            ||.|..|||.|||||:...|..:|:.||.:.|..|.|.|.....|..|::
Human   323 PYKCEECGKAFSLSSTLKKHKIVHTGEKLYTCEECGKAFTFSSTLNTHKR 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zaf1	NP_731602.1	zf-AD	9..79	CDD:214871
		SFP1	<161..320	CDD:227516	51/199 (26%)
		C2H2 Zn finger	229..249	CDD:275368	6/19 (32%)
		C2H2 Zn finger	257..277	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..293	CDD:463886	13/50 (26%)
		C2H2 Zn finger	285..305	CDD:275368	8/46 (17%)
		C2H2 Zn finger	313..333	CDD:275368	10/19 (53%)
		C2H2 Zn finger	341..359	CDD:275368	6/17 (35%)
ZNF716	NP_001152751.1	KRAB	16..76	CDD:214630	4/9 (44%)
		C2H2 Zn finger	160..179	CDD:275368	1/18 (6%)
		C2H2 Zn finger	187..207	CDD:275368	1/19 (5%)
		COG5048	211..>494	CDD:227381	58/162 (36%)
		C2H2 Zn finger	215..235	CDD:275368	6/19 (32%)
		C2H2 Zn finger	243..263	CDD:275368	8/19 (42%)
		C2H2 Zn finger	298..318	CDD:275368	7/19 (37%)
		C2H2 Zn finger	326..346	CDD:275368	10/19 (53%)
		C2H2 Zn finger	354..374	CDD:275368	6/19 (32%)
		C2H2 Zn finger	382..402	CDD:275368
		C2H2 Zn finger	410..430	CDD:275368
		C2H2 Zn finger	438..458	CDD:275368
		C2H2 Zn finger	466..486	CDD:275368