DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6808 and CG4854

DIOPT Version :9

Sequence 1:	NP_001247055.1	Gene:	CG6808 / 41394	FlyBaseID:	FBgn0037921	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	364	Identity:	112/364 - (30%)
Similarity:	159/364 - (43%)	Gaps:	77/364 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 CRTCRKKGTQSTLQSLFESNAHKLLISYAGTSVKPDDGLPDQICTVCLMQLEEVDRFLSACKQSD 74
            ||.|..:....:|... |.:....:....|..:......|::|||.|.:.|.      :|.|
  Fly    12 CRICLVQPKDESLMPT-EPDFPDKIKRCTGVELSESPDWPNRICTSCALLLR------AALK--- 66

  Fly    75 AHLRSLVRQTLSSASAFETLEDKDQLEQKKRARKQNISGRLIEENPINFKTQENALETTKDDEIL 139
              ||||.:||           :||..|||            ::|  ||.:...:..||.|..|
  Fly    67 --LRSLCQQT-----------EKDLKEQK------------LQE--INIEIVHDEQETKKKTE-- 102

  Fly   140 PINKFSSDFVFDLNVNAENEKDIHQEDYTISDMDLDREISDQNYSETY--SQESSAATD------ 196
                               .:|:.:.:.|.||.:|:.|..| :|..|.  |::.:.:.|
  Fly   103 -------------------SRDLSKNEATGSDSELEYEYLD-SYDVTLESSEDVACSADELVSIE 147

  Fly   197 -SIQETSEDYHNLEPS----ADYVIDLGVACEPDKYRCKICSNTYRCLSQLNAHSQVHRKEKDHQ 256
             :|....|..::|.|.    .|.  |.|.|.   .:.|.||:|.|....:|..|.:||..:|.|:
  Fly   148 PAISAPEESVYSLSPKPVTFEDE--DSGQAA---SFTCNICNNVYSERVKLTNHMKVHSAKKPHE 207

  Fly   257 CEVCQKTFRAACNLKTHMRTHTGEKPYQCCYCSRRFADNSTHRKHERLHTNERPYACNICGKTFS 321
            ||:|.|.||....|..||.||||.:||:|.||..||||.||..||:|:|||||||.|..|.::|.
  Fly   208 CEICHKRFRQTPQLARHMNTHTGNRPYKCDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFG 272

  Fly   322 LSSSRNAHYYLHSSEKSHKCLMCKKEFRLKHQLTAHEKS 360
            .|:....|...|:.|:...|..|:|.|...|...:||||
  Fly   273 YSNVLRVHLKTHTGERPFSCQYCQKSFSQLHHKNSHEKS 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6808	NP_001247055.1	zf-AD	9..79	CDD:214871	15/68 (22%)
		C2H2 Zn finger	229..249	CDD:275368	7/19 (37%)
		zf-C2H2	255..277	CDD:278523	10/21 (48%)
		C2H2 Zn finger	257..277	CDD:275368	9/19 (47%)
		zf-H2C2_2	269..293	CDD:290200	13/23 (57%)
		C2H2 Zn finger	285..305	CDD:275368	12/19 (63%)
		zf-H2C2_2	299..321	CDD:290200	12/21 (57%)
		C2H2 Zn finger	313..333	CDD:275368	5/19 (26%)
		C2H2 Zn finger	341..359	CDD:275368	6/17 (35%)
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	10/45 (22%)
		C2H2 Zn finger	180..200	CDD:275368	7/19 (37%)
		zf-H2C2_2	193..217	CDD:290200	11/23 (48%)
		COG5048	201..>258	CDD:227381	30/56 (54%)
		C2H2 Zn finger	208..228	CDD:275368	9/19 (47%)
		zf-H2C2_2	221..244	CDD:290200	13/22 (59%)
		C2H2 Zn finger	236..256	CDD:275368	12/19 (63%)
		zf-H2C2_2	251..273	CDD:290200	13/21 (62%)
		C2H2 Zn finger	264..284	CDD:275368	5/19 (26%)
		zf-H2C2_2	277..301	CDD:290200	7/23 (30%)
		C2H2 Zn finger	292..312	CDD:275368	9/20 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471442
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I3338
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.890