DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6808 and CG4424

DIOPT Version :9

Sequence 1:	NP_001247055.1	Gene:	CG6808 / 41394	FlyBaseID:	FBgn0037921	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	388	Identity:	113/388 - (29%)
Similarity:	173/388 - (44%)	Gaps:	78/388 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEISIK-WSMCRTCRKKGTQSTLQSLFESNAHKL---------LISYAGTSVK---PDDGLPDQI 52
            |||.:. .::||||.:.| ::.:.|:|::...:|         :.|.:|..::   .::.||.:|
  Fly     1 MEIRLNMMTLCRTCLQDG-EAHMVSIFQTADDRLPGGVSLCDKIESLSGIQIRATAKEEVLPTRI 64

  Fly    53 CTVCLMQLEEVDRFLSACKQSDAHLRSLVRQTLSSASAFETLEDKDQLEQKKRARKQNISGRLIE 117
            |..|...|....:|...|::|:..||..|              .||.:|       |.:...:::
  Fly    65 CLRCKAFLTLAHKFRQICQRSNEFLREYV--------------IKDAVE-------QGVVKEVVQ 108

  Fly   118 E----NPINFKTQENALETTKDDEILPINKFSSDFVFDLNVNAENEKDIHQEDYTISDMDLDREI 178
            :    .|...:|::  || ..:||:|....:|::...:...:...||    |..|:    |..|:
  Fly   109 QTRPSTPPPIETEQ--LE-PPEDEVLEEGVWSTEDPIEETPHGPAEK----ERPTV----LTVEM 162

  Fly   179 SDQNYSETYSQESSAATDSIQETSEDYHNLEPSADYVIDLGVACEPDKYRCKICSNTYRCLSQLN 243
            ....|....|....|...::                        :...:.|.||.|.|...|.|:
  Fly   163 LPAPYPPPASTPPPAPAGAV------------------------KGKLHVCAICGNGYPRKSTLD 203

  Fly   244 AHSQVHRKEKDHQCEVCQKTFRAACNLKTHMRTHTGEKPYQCCYCSRRFADNSTHRKHERLHTNE 308
            .|.:.|..|:.::||:|.|:|.....||.|:|.|||.|||.|.||.|.|||.::..||||.|.||
  Fly   204 THMRRHNDERPYECEICHKSFHVNYQLKRHIRQHTGAKPYTCQYCQRNFADRTSLVKHERTHRNE 268

  Fly   309 RPYACNICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEFRLKHQLTAHEKSLAH----RLIA 367
            |||||..|||.|:.:|....||..|:.||.|.|.:|.|.|...|.|.||.::..|    ||.|
  Fly   269 RPYACKTCGKKFTYASVLKMHYKTHTGEKPHICQLCNKSFARIHNLVAHLQTQQHINDPRLTA 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6808	NP_001247055.1	zf-AD	9..79	CDD:214871	20/81 (25%)
		C2H2 Zn finger	229..249	CDD:275368	8/19 (42%)
		zf-C2H2	255..277	CDD:278523	9/21 (43%)
		C2H2 Zn finger	257..277	CDD:275368	9/19 (47%)
		zf-H2C2_2	269..293	CDD:290200	14/23 (61%)
		C2H2 Zn finger	285..305	CDD:275368	11/19 (58%)
		zf-H2C2_2	299..321	CDD:290200	15/21 (71%)
		C2H2 Zn finger	313..333	CDD:275368	8/19 (42%)
		C2H2 Zn finger	341..359	CDD:275368	8/17 (47%)
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	21/82 (26%)
		C2H2 Zn finger	189..209	CDD:275368	8/19 (42%)
		DUF45	<204..281	CDD:302795	40/76 (53%)
		COG5048	210..>345	CDD:227381	58/122 (48%)
		C2H2 Zn finger	217..237	CDD:275368	9/19 (47%)
		C2H2 Zn finger	245..265	CDD:275368	11/19 (58%)
		zf-H2C2_2	257..282	CDD:290200	16/24 (67%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		zf-H2C2_2	286..310	CDD:290200	10/23 (43%)
		C2H2 Zn finger	301..320	CDD:275368	8/18 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471438
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I3338
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.890