DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6808 and CG5245

DIOPT Version :9

Sequence 1:	NP_001247055.1	Gene:	CG6808 / 41394	FlyBaseID:	FBgn0037921	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_650197.1	Gene:	CG5245 / 41530	FlyBaseID:	FBgn0038047	Length:	501	Species:	Drosophila melanogaster

Alignment Length:	342	Identity:	87/342 - (25%)
Similarity:	138/342 - (40%)	Gaps:	54/342 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 SYAGTSVKPDDGLPDQICTVCLMQLEEVDRFLSACKQSDAHLRSLVRQTLSSASAFETLEDKDQL 100
            || |..::|..|:|.:               |..||...|..|.|.:||    ..|:..:.
  Fly    47 SY-GKDLEPVKGVPSK---------------LKTCKSKIAKKRPLRKQT----DTFKCTQC---- 87

  Fly   101 EQKKRARKQNISGRL---IEENPI-------NFKTQENALETTKDDEILP--INKFSSDFVFDLN 153
             ||...||:|:...|   .||.|.       :|..:.:........|..|  .:..|..|    .
  Fly    88 -QKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYKRHLLKHEKRPHKCSHCSKTF----T 147

  Fly   154 VNAENEKDIHQE------DYTISDMDLDREISDQNYSETYSQESSAATDSIQETSEDYHNLEPSA 212
            .|:..::.:|:.      ..|.......|:...|.:..|:|:|........::..::..:|:.
  Fly   148 QNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQE-- 210

  Fly   213 DYVIDLGVACEPDKYRCKICSNTYRCLSQLNAHSQVHRKEKDHQCEVCQKTFRAACNLKTHMRTH 277
                .|....|...::|..||.:::..|.|..|...| .|:..:|..|.|||....:|:.|:|.|
  Fly   211 ----HLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH-AERSFKCTQCPKTFLQNDSLQIHLRVH 270

  Fly   278 TGEKPYQCCYCSRRFADNSTHRKHERLHTNERPYACNICGKTFSLSSSRNAHYYLHSSEKSHKCL 342
            .||.|::|.:||..||.||..:.|...|..:.|..|:.|..||::.|....|..||:.|:.:||.
  Fly   271 AGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCA 335

  Fly   343 MCKKEFRLKHQLTAHEK 359
            .|.|.|..|..|..|::
  Fly   336 ECSKSFFKKSHLVEHQQ 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6808	NP_001247055.1	zf-AD	9..79	CDD:214871	10/42 (24%)
		C2H2 Zn finger	229..249	CDD:275368	6/19 (32%)
		zf-C2H2	255..277	CDD:278523	8/21 (38%)
		C2H2 Zn finger	257..277	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..293	CDD:290200	10/23 (43%)
		C2H2 Zn finger	285..305	CDD:275368	8/19 (42%)
		zf-H2C2_2	299..321	CDD:290200	6/21 (29%)
		C2H2 Zn finger	313..333	CDD:275368	6/19 (32%)
		C2H2 Zn finger	341..359	CDD:275368	7/17 (41%)
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	76/299 (25%)
		C2H2 Zn finger	84..104	CDD:275368	6/24 (25%)
		C2H2 Zn finger	112..132	CDD:275368	1/19 (5%)
		C2H2 Zn finger	139..159	CDD:275368	4/23 (17%)
		C2H2 Zn finger	167..187	CDD:275368	3/19 (16%)
		zf-H2C2_2	179..204	CDD:290200	4/24 (17%)
		C2H2 Zn finger	195..215	CDD:275368	2/25 (8%)
		C2H2 Zn finger	223..243	CDD:275368	6/19 (32%)
		C2H2 Zn finger	250..270	CDD:275368	8/19 (42%)
		C2H2 Zn finger	278..298	CDD:275368	8/19 (42%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		C2H2 Zn finger	334..354	CDD:275368	7/19 (37%)
		C2H2 Zn finger	362..382	CDD:275368
		C2H2 Zn finger	390..410	CDD:275368
		C2H2 Zn finger	418..438	CDD:275368
		C2H2 Zn finger	446..466	CDD:275368
		C2H2 Zn finger	474..492	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471459
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840