DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6808 and CG14711

DIOPT Version :9

Sequence 1:	NP_001247055.1	Gene:	CG6808 / 41394	FlyBaseID:	FBgn0037921	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster

Alignment Length:	387	Identity:	110/387 - (28%)
Similarity:	170/387 - (43%)	Gaps:	54/387 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KWSMCRTCRKKGTQS-TLQSLFESN---AHKLL--ISYAGTSVK--PDDGLPDQICTVCLMQLEE 62
            ::.:||.|..:...| .:..||:.|   ..:|:  |...| |:|  |...:|..:|..|:.:|..
  Fly     3 EYMLCRICLTEDINSEAMAPLFDDNDAQCRELVRKIEEVG-SIKLVPLQNIPSMLCYSCVERLTS 66

  Fly    63 VDRFLSACKQSDAHLRSLVRQTLSSASAFETLED-----KDQLEQKKRARKQNISG-------RL 115
            ..:|...|::|:   |:.....:.:....|..::     .|.:|....:....|.|       ..
  Fly    67 AHKFRELCQESE---RTFATNVVKAEMKSEPTDEVPHVVADNIEYIYESANDFIDGVEDDIGMEN 128

  Fly   116 IEENPINFKTQE--NALETT------KDDEILPINKFSSDFVFDLNVNAENEKDIHQEDYTISDM 172
            |.|.|:.....|  .|.||:      .:|::|..|...||:   ..:....:..:.:...|....
  Fly   129 IMEEPLEDGVGETSQAYETSTVVDDLDEDDLLVPNSTDSDY---QPIERCRKAKVRKTRMTKRGR 190

  Fly   173 DLDREISDQNYSETYSQESSAATDSIQETSEDYHNLEPSADYVIDLGVACEPDKYRCKICSNTYR 237
            ...|..| ..:..::|:|......|.:.:.|           |....:.||       ||.|.|.
  Fly   191 GRPRGAS-SGHPRSFSEERPPVQASFKSSPE-----------VSSTNIMCE-------ICGNIYS 236

  Fly   238 CLSQLNAHSQVHRKEKDHQCEVCQKTFRAACNLKTHMRTHTGEKPYQCCYCSRRFADNSTHRKHE 302
            ..:.||.|.:.|..||..:||:|.|:|.....|..|:|.||||||:.|.||:|.|||.|::.:||
  Fly   237 KRAALNIHMRRHMAEKPFKCEICSKSFAGPSELNRHIRVHTGEKPFLCKYCNRSFADRSSNIRHE 301

  Fly   303 RLHTNERPYACNICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEFRLKHQLTAHEKSLAHR 364
            |.||||||:.|:.|||.||.|:....|...|:.||...|.:|.|.|..||||..|..::.|:
  Fly   302 RTHTNERPFTCSTCGKAFSYSNVLKNHMLTHTGEKPFLCRVCNKTFSRKHQLDQHLGTMTHQ 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6808	NP_001247055.1	zf-AD	9..79	CDD:214871	20/77 (26%)
		C2H2 Zn finger	229..249	CDD:275368	7/19 (37%)
		zf-C2H2	255..277	CDD:278523	8/21 (38%)
		C2H2 Zn finger	257..277	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..293	CDD:290200	13/23 (57%)
		C2H2 Zn finger	285..305	CDD:275368	11/19 (58%)
		zf-H2C2_2	299..321	CDD:290200	13/21 (62%)
		C2H2 Zn finger	313..333	CDD:275368	8/19 (42%)
		C2H2 Zn finger	341..359	CDD:275368	9/17 (53%)
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071	21/78 (27%)
		C2H2 Zn finger	228..248	CDD:275368	9/26 (35%)
		zf-H2C2_2	240..264	CDD:290200	10/23 (43%)
		COG5048	249..>362	CDD:227381	53/112 (47%)
		C2H2 Zn finger	256..276	CDD:275368	8/19 (42%)
		zf-H2C2_2	268..292	CDD:290200	13/23 (57%)
		C2H2 Zn finger	284..304	CDD:275368	11/19 (58%)
		zf-H2C2_2	299..321	CDD:290200	14/21 (67%)
		C2H2 Zn finger	312..332	CDD:275368	8/19 (42%)
		zf-H2C2_2	325..349	CDD:290200	8/23 (35%)
		C2H2 Zn finger	340..362	CDD:275368	9/21 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I3338
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24381
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.060