DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG6808 and Zif

DIOPT Version :9

Sequence 1:NP_001247055.1 Gene:CG6808 / 41394 FlyBaseID:FBgn0037921 Length:375 Species:Drosophila melanogaster
Sequence 2:NP_001189188.1 Gene:Zif / 40795 FlyBaseID:FBgn0037446 Length:388 Species:Drosophila melanogaster


Alignment Length:389 Identity:102/389 - (26%)
Similarity:172/389 - (44%) Gaps:54/389 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MEISIKWSMCRTCRKKGTQSTLQSL------FESNAHKLLISYAGTS---VKPDDGLPDQICTVC 56
            |.:.:....||.|..:..:  ||.|      .|.:.:::||...|.|   :...:.:||.||..|
  Fly     1 MRVELTPQTCRVCLAQSER--LQRLDEIREEGEESPNEMLIQLLGVSYSNLNDREHIPDGICKSC 63

  Fly    57 LMQLEEVDRFLSACKQSDAHLRSLVRQT-LSSASAFETLEDKD----QLEQKKRARKQNISGRLI 116
            .::|....:|.....:....:....|:. |...|....::::|    |.:::....::..:|   
  Fly    64 KVELNMAYQFREKALRKQMEIEEYCRELGLLDESDVMMIKEEDGSQQQCDEEMYILEETTTG--- 125

  Fly   117 EENPINFKTQENALETTKDDEILPINKFSSDFVFDLNVNAENEKDIHQEDYTISDMDLDR-EI-- 178
            ||.....|..|..||....|:    .:...|.:           :..:::||| :|:.|: ||  
  Fly   126 EEEHQEEKGHEEYLEVDTSDQ----QECIGDTI-----------EYLEDNYTI-EMNSDQTEIVL 174

  Fly   179 -SDQNYSETYSQE---SSAATDSIQ----ETSEDYHNLEPSADYVIDLGVACEPDKYRCKICSNT 235
             |::.|.||.||:   ..||..|::    ......::|..|.        ..|...|.|.:|.|.
  Fly   175 ESEKQYEETPSQQLALQEAAKASLKARRGRVRRGLNSLTTSD--------GTEKGGYICDVCGNF 231

  Fly   236 YRCLSQLNAHSQVHRKEKDHQCEVCQKTFRAACNLKTHMRTHTGEKPYQCCYCSRRFADNSTHRK 300
            |....::..|.:.|.....:.||:|...|:....|:.||.:|||.|||:|.:|||:|...|..:.
  Fly   232 YEKRGRMMEHRRRHDGICQYACELCDAKFQVREQLRKHMYSHTGSKPYKCSFCSRQFFYESVLKS 296

  Fly   301 HERLHTNERPYACNICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEFRLKHQLTAHEKSLAHR 364
            ||.:|...:||.|.:|.|.|:.:.|...|..:||..|.::|..|.|:|||.|.:..||::..|:
  Fly   297 HENVHRGIKPYVCKVCDKAFAYAHSLTKHELIHSDIKLYRCDYCNKDFRLLHHMRQHEETKLHQ 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6808NP_001247055.1 zf-AD 9..79 CDD:214871 18/78 (23%)
C2H2 Zn finger 229..249 CDD:275368 5/19 (26%)
zf-C2H2 255..277 CDD:278523 7/21 (33%)
C2H2 Zn finger 257..277 CDD:275368 7/19 (37%)
zf-H2C2_2 269..293 CDD:290200 13/23 (57%)
C2H2 Zn finger 285..305 CDD:275368 8/19 (42%)
zf-H2C2_2 299..321 CDD:290200 8/21 (38%)
C2H2 Zn finger 313..333 CDD:275368 6/19 (32%)
C2H2 Zn finger 341..359 CDD:275368 8/17 (47%)
ZifNP_001189188.1 zf-AD 9..87 CDD:285071 18/79 (23%)
C2H2 Zn finger 225..245 CDD:275368 5/19 (26%)
COG5048 <250..369 CDD:227381 43/111 (39%)
C2H2 Zn finger 253..273 CDD:275368 7/19 (37%)
zf-H2C2_2 266..288 CDD:290200 13/21 (62%)
C2H2 Zn finger 281..301 CDD:275368 8/19 (42%)
zf-H2C2_2 294..318 CDD:290200 9/23 (39%)
C2H2 Zn finger 309..329 CDD:275368 6/19 (32%)
C2H2 Zn finger 337..353 CDD:275368 7/15 (47%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.910

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