DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6808 and Phs

DIOPT Version :9

Sequence 1:	NP_001247055.1	Gene:	CG6808 / 41394	FlyBaseID:	FBgn0037921	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_648789.3	Gene:	Phs / 39697	FlyBaseID:	FBgn0036522	Length:	971	Species:	Drosophila melanogaster

Alignment Length:	405	Identity:	101/405 - (24%)
Similarity:	161/405 - (39%)	Gaps:	100/405 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RKKGTQSTLQSLFESNA-------------------------HKLLISYAGTSVKPDDGLPDQIC 53
            :|.||||..:|  |:|.                         .:|.|..||.:....|...:|
  Fly   425 KKDGTQSAQKS--ETNPKHLENAETNSKDNTESVALKETIHDKQLTIDEAGKAGTQKDDNSNQ-- 485

  Fly    54 TVCLMQLEEVDRFLSACKQSDAHLRSLVRQTLSSASAFETLEDKDQLEQ-------KKRARKQNI 111
                .||::.:......|..|.     |.|.:...||    :|..|:.:       :||.||:..
  Fly   486 ----KQLDKSEANAGKSKMVDQ-----VHQQMPVESA----KDHQQMTEEPTNSTKRKRGRKERK 537

  Fly   112 SGRLIEENPINFKTQENALETTKDDEILPINKFSS-----DFVFDLNVNAENEKDIHQEDYTISD 171
            |     ..|:.....:..:   |::..||..:...     |:|.::       ||..::|..:.:
  Fly   538 S-----PTPVLIPLGDKEI---KEEPELPERRMRKSRQHVDYVVEI-------KDEEEDDDEVEE 587

  Fly   172 MDLDREISDQNYSETYSQESSAATDSI----QETSED-YHNLEPSADYVIDLGVACEPDKYRCKI 231
            .::     |.:.|.|.|..:|:..:|.    :|:||: .||           |:.   ..:.|..
  Fly   588 AEV-----DDDSSATISPHNSSTDESFTSIKRESSEESQHN-----------GIG---GIHTCNF 633

  Fly   232 CSNTYRCLSQLNAHSQVHRKEKDHQCEVCQKTFRAACNLKTHMRTHTGEKPYQCCYCSRRFA--- 293
            |..|::..|::..|.::|..||.:.|..|.:.||....|..|...|..||.|:|..||...|
  Fly   634 CGKTFKRFSRMQDHLRLHTGEKPYVCGQCGRAFRLKMRLVEHQLRHRAEKAYKCDICSMPLATKQ 698

  Fly   294 DNSTHRKHERLHTNERPYACNICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEFRLKHQLTAHE 358
            |.|.|.:|   |.|:|.|.|:.|.|.|..||..:.|..:|:.||.:.|.:|.|.||.:..|..|.
  Fly   699 DLSLHMRH---HKNDRRYKCDKCNKGFVRSSDLSIHVRIHTGEKPYSCDLCGKAFRARQNLVVHR 760

  Fly   359 KS-LAHRLIAKEYSD 372
            :: |..:.|..|..|
  Fly   761 RTHLGDKPIQCELCD 775

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6808	NP_001247055.1	zf-AD	9..79	CDD:214871	18/89 (20%)
		C2H2 Zn finger	229..249	CDD:275368	5/19 (26%)
		zf-C2H2	255..277	CDD:278523	6/21 (29%)
		C2H2 Zn finger	257..277	CDD:275368	6/19 (32%)
		zf-H2C2_2	269..293	CDD:290200	9/23 (39%)
		C2H2 Zn finger	285..305	CDD:275368	8/22 (36%)
		zf-H2C2_2	299..321	CDD:290200	8/21 (38%)
		C2H2 Zn finger	313..333	CDD:275368	7/19 (37%)
		C2H2 Zn finger	341..359	CDD:275368	7/17 (41%)
Phs	NP_648789.3	COG5048	<594..787	CDD:227381	62/199 (31%)
		C2H2 Zn finger	631..651	CDD:275368	5/19 (26%)
		zf-H2C2_2	644..666	CDD:290200	6/21 (29%)
		zf-H2C2_2	699..724	CDD:290200	12/27 (44%)
		zf-C2H2	713..735	CDD:278523	8/21 (38%)
		C2H2 Zn finger	715..735	CDD:275368	7/19 (37%)
		zf-H2C2_2	727..750	CDD:290200	7/22 (32%)
		C2H2 Zn finger	743..763	CDD:275368	7/19 (37%)
		zf-H2C2_2	755..780	CDD:290200	6/21 (29%)
		C2H2 Zn finger	771..791	CDD:275368	2/5 (40%)
		zf-H2C2_2	783..808	CDD:290200
		C2H2 Zn finger	799..816	CDD:275370
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3304
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.950