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Protein Alignment Zaf1 and ZNF546

DIOPT Version :10

Sequence 1:	NP_731602.1	Gene:	Zaf1 / 41394	FlyBaseID:	FBgn0037921	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_848639.2	Gene:	ZNF546 / 339327	HGNCID:	28671	Length:	836	Species:	Homo sapiens

Alignment Length:	398	Identity:	91/398 - (22%)
Similarity:	157/398 - (39%)	Gaps:	98/398 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 WSMCRTCRKKGTQSTLQSLFESNAHKLLISYAGTSVKPDDGLPDQICTVCLMQLEEVDRFLSACK 71
            |.:.|    :||::....|......|.|:|            ...:|.:.|.||:..::
Human   119 WIVMR----EGTRNWFTDLEYKYITKNLLS------------EKNVCKIYLSQLQTGEK------ 161

  Fly    72 QSDAHLRSLVRQTLSSASAFET-LEDKDQLEQKKRARKQNISGRLIEE---NPINFK--TQENAL 130
                     .:.|:...:.|.. |:.|.:.|:::|.:...:|..||::   :|::.|  .:|.:.
Human   162 ---------SKNTIHEDTIFRNGLQCKHEFERQERHQMGCVSQMLIQKQISHPLHPKIHAREKSY 217

  Fly   131 ETTKDDEILPINKFSSDFVFDLNVNAENEKDIHQEDYTISDMDL---DREISDQNYSETYSQ--- 189
            |.                       .|..|...|:.|.|..:.:   :|........:.:.:
Human   218 EC-----------------------KECRKAFRQQSYLIQHLRIHTGERPYKCMECGKAFCRVGD 259

  Fly   190 ----ESSAATDSIQETSE-------DYHNLEPS---------------------ADYVIDLGVAC 222
                .:..|.:...|..|       .||..|..                     .|..:...:..
Human   260 LRVHHTIHAGERPYECKECGKAFRLHYHLTEHQRIHSGVKPYECKECGKAFSRVRDLRVHQTIHA 324

  Fly   223 EPDKYRCKICSNTYRCLSQLNAHSQVHRKEKDHQCEVCQKTFRAACNLKTHMRTHTGEKPYQCCY 287
            ....|.||.|...:|...||..|.::|..|:.::|:||.||||...::..|.:.|||.|||:|..
Human   325 GERPYECKECGKAFRLHYQLTEHQRIHTGERPYECKVCGKTFRVQRHISQHQKIHTGVKPYKCNE 389

  Fly   288 CSRRFADNSTHRKHERLHTNERPYACNICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEFRLKH 352
            |.:.|:..|...:|:::||.|:||.|..|||:||..:....|..:|:.||.::|..|.|.|||:.
Human   390 CGKAFSHGSYLVQHQKIHTGEKPYECKECGKSFSFHAELARHRRIHTGEKPYECRECGKAFRLQT 454

  Fly   353 QLTAHEKS 360
            :||.|.::
Human   455 ELTRHHRT 462

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.