Protein Alignment Zaf1 and ZNF658

DIOPT Version :10

• Sequence 1: NP_731602.1
• Gene: Zaf1 / 41394
• FlyBaseID: FBgn0037921
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_149350.3
• Gene: ZNF658 / 26149
• HGNCID: 25226
• Length: 1059
• Species: Homo sapiens
• Alignment Length: 175
• Identity: 67/175 - (38%)
• Similarity: 91/175 - (52%)
• Gaps: 21/175 - (12%)

  Fly   185 ETYSQESSAATDSIQETSEDYHNLEPSADYVIDLGVACEPDKYRCKICSNTYRCLSQLNAHSQVH 249
            :|:||:|..:......|.|                   :|  |.|.:|..|:...:.|..|.::|
Human   777 KTFSQKSYLSGHERIHTGE-------------------KP--YECNVCGKTFVYKAALIVHQRIH 820

  Fly   250 RKEKDHQCEVCQKTFRAACNLKTHMRTHTGEKPYQCCYCSRRFADNSTHRKHERLHTNERPYACN 314
            ..||.::|..|.|||....:|..|.|.|||||||:|..|.:.|||||..|.|.|:||.|:||.||
Human   821 TGEKPYECNQCGKTFSQRTHLCAHQRIHTGEKPYECNECGKTFADNSALRAHHRIHTGEKPYECN 885

  Fly   315 ICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEFRLKHQLTAHEK 359
            .||||||.:|...||....|.||.::|..|.|.|..|..::||::
Human   886 DCGKTFSKTSHLRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQR 930

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zaf1	NP_731602.1	zf-AD	9..79	CDD:214871
		SFP1	<161..320	CDD:227516	51/134 (38%)
		C2H2 Zn finger	229..249	CDD:275368	5/19 (26%)
		C2H2 Zn finger	257..277	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..293	CDD:463886	12/23 (52%)
		C2H2 Zn finger	285..305	CDD:275368	10/19 (53%)
		C2H2 Zn finger	313..333	CDD:275368	11/19 (58%)
		C2H2 Zn finger	341..359	CDD:275368	7/17 (41%)
ZNF658	NP_149350.3	KRAB	8..68	CDD:214630
		C2H2 Zn finger	279..296	CDD:275368
		C2H2 Zn finger	299..319	CDD:275368
		C2H2 Zn finger	328..347	CDD:275368
		C2H2 Zn finger	355..375	CDD:275368
		COG5048	371..789	CDD:227381	4/11 (36%)
		C2H2 Zn finger	389..406	CDD:275368
		C2H2 Zn finger	414..434	CDD:275368
		C2H2 Zn finger	442..462	CDD:275368
		C2H2 Zn finger	520..540	CDD:275368
		C2H2 Zn finger	548..568	CDD:275368
		C2H2 Zn finger	576..596	CDD:275368
		C2H2 Zn finger	604..624	CDD:275368
		COG5048	628..1044	CDD:227381	67/175 (38%)
		C2H2 Zn finger	632..652	CDD:275368
		C2H2 Zn finger	660..680	CDD:275368
		C2H2 Zn finger	688..708	CDD:275368
		C2H2 Zn finger	716..736	CDD:275368
		C2H2 Zn finger	744..764	CDD:275368
		C2H2 Zn finger	772..792	CDD:275368	4/14 (29%)
		C2H2 Zn finger	800..820	CDD:275368	5/19 (26%)
		C2H2 Zn finger	828..848	CDD:275368	8/19 (42%)
		C2H2 Zn finger	856..876	CDD:275368	10/19 (53%)
		C2H2 Zn finger	884..903	CDD:275368	11/18 (61%)
		C2H2 Zn finger	912..932	CDD:275368	7/19 (37%)
		C2H2 Zn finger	940..960	CDD:275368
		C2H2 Zn finger	968..988	CDD:275368
		C2H2 Zn finger	996..1016	CDD:275368
		C2H2 Zn finger	1024..1045	CDD:275368