Protein Alignment Zaf1 and ZNF600

DIOPT Version :10

• Sequence 1: NP_731602.1
• Gene: Zaf1 / 41394
• FlyBaseID: FBgn0037921
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_001308795.1
• Gene: ZNF600 / 162966
• HGNCID: 30951
• Length: 791
• Species: Homo sapiens
• Alignment Length: 216
• Identity: 76/216 - (35%)
• Similarity: 100/216 - (46%)
• Gaps: 32/216 - (14%)

  Fly   185 ETYSQESSAATDSIQETSEDYHNLEPSADYVIDLGVACEPDK--------YRCKICSNTYRCLSQ 241
            :|:.|.|.........|.|..:..| ..:.|...|...|..|        |:||:|...:.|.|.
Human   490 KTFGQNSDLLIHKSIHTGEQPYKYE-ECEKVFSCGSTLETHKIIHTGEKPYKCKVCDKAFACHSY 553

  Fly   242 LNAHSQVHRKEKDHQCEVCQKTFRAACNLKTHMRTHTGEKPYQCCYCSRRFADNSTHRKHERLHT 306
            |..|:::|..||.::|..|.||||....|.:|.|.|:|||||:|..||:.|:..|....|.|||:
Human   554 LAKHTRIHSGEKPYKCNECSKTFRLRSYLASHRRVHSGEKPYKCNECSKTFSQRSYLHCHRRLHS 618

  Fly   307 NERPYACNICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEFRLKHQLTAHEK------------ 359
            .|:||.||.||||||...|...|..||:.|||:||.:|.|.|.....|..|.:
Human   619 GEKPYKCNECGKTFSHKPSLVHHRRLHTGEKSYKCTVCDKAFVRNSYLARHTRIHTAEKPYKCNE 683

  Fly   360 -----------SLAHRLIAKE 369
                       ||.||:.|.|
Human   684 CGKAFNQQSQLSLHHRIHAGE 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zaf1	NP_731602.1	zf-AD	9..79	CDD:214871
		SFP1	<161..320	CDD:227516	53/142 (37%)
		C2H2 Zn finger	229..249	CDD:275368	7/19 (37%)
		C2H2 Zn finger	257..277	CDD:275368	9/19 (47%)
		zf-H2C2_2	269..293	CDD:463886	12/23 (52%)
		C2H2 Zn finger	285..305	CDD:275368	7/19 (37%)
		C2H2 Zn finger	313..333	CDD:275368	10/19 (53%)
		C2H2 Zn finger	341..359	CDD:275368	6/17 (35%)
ZNF600	NP_001308795.1	KRAB	24..60	CDD:460171
		COG5048	<154..503	CDD:227381	3/12 (25%)
		C2H2 Zn finger	233..253	CDD:275368
		C2H2 Zn finger	261..281	CDD:275368
		C2H2 Zn finger	289..309	CDD:275368
		C2H2 Zn finger	317..337	CDD:275368
		COG5048	341..748	CDD:227381	76/216 (35%)
		C2H2 Zn finger	345..365	CDD:275368
		C2H2 Zn finger	373..393	CDD:275368
		C2H2 Zn finger	401..421	CDD:275368
		C2H2 Zn finger	429..449	CDD:275368
		C2H2 Zn finger	457..477	CDD:275368
		C2H2 Zn finger	485..505	CDD:275368	3/14 (21%)
		C2H2 Zn finger	513..533	CDD:275368	5/20 (25%)
		C2H2 Zn finger	541..561	CDD:275368	7/19 (37%)
		C2H2 Zn finger	569..589	CDD:275368	9/19 (47%)
		C2H2 Zn finger	597..617	CDD:275368	7/19 (37%)
		C2H2 Zn finger	625..645	CDD:275368	10/19 (53%)
		C2H2 Zn finger	653..673	CDD:275368	6/19 (32%)
		C2H2 Zn finger	681..701	CDD:275368	4/19 (21%)
		C2H2 Zn finger	709..729	CDD:275368
		C2H2 Zn finger	737..757	CDD:275368
		zf-H2C2_2	749..774	CDD:463886
		C2H2 Zn finger	765..785	CDD:275368