DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG14710 and Zfp24

DIOPT Version :9

Sequence 1:NP_650092.4 Gene:CG14710 / 41393 FlyBaseID:FBgn0037920 Length:415 Species:Drosophila melanogaster
Sequence 2:NP_001344376.1 Gene:Zfp24 / 59057 MGIID:1929704 Length:368 Species:Mus musculus


Alignment Length:415 Identity:99/415 - (23%)
Similarity:158/415 - (38%) Gaps:115/415 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 EESQMICLFGDKGESDLRKKLE-------------------LCCRIRVRQ-----SPQLPEKACN 58
            |:|.:|....|:.|..||.|||                   ...|.|.||     ||. |.:|.:
Mouse     8 EDSILIIPNPDEEEKILRVKLEEDPDGEEGSSISWNHLPDPEVFRQRFRQFGYQDSPG-PREAVS 71

  Fly    59 SCCEFVQMWFNFRQMCLNSQVYWETSSSERPEALAQASDAE------YMLYLYENLHLKLGTENQ 117
            ...|..::|.                   |||...:....|      ::..|.:.|...:...:.
Mouse    72 QLRELCRLWL-------------------RPETHTKEQILELVVLEQFVAILPKELQTWVREHHP 117

  Fly   118 E--KEEITAIEEGDEQQED---------QSQEVLDFNGFIINESIEEDEEPNTESPEQILIS--- 168
            |  :|.:..:|:.:.:.:|         |.:|||      :.|...:::.....|.|...:.   
Mouse   118 ENGEEAVAVLEDLESELDDPGQPVSLRRQKREVL------VEEITSQEDAQGLPSSELDAVENQL 176

  Fly   169 -------HMDSYVDDQQMEELIDDKGELV--EELSNANTFYE----VEYGDEELLMSSAPSPHPS 220
                   |...:.||....|    .|.|.  :|:::|...:|    :..|..:|.          
Mouse   177 KWASWELHSLRHCDDDATTE----NGALAPKQEMASAGESHEGPGTLNIGVPQLF---------- 227

  Fly   221 FKMDKQKPGRPRKPDAELKFKRKDINAKERGNQPKCKEEEKFMCILCGNVFYKKSVFTAHMMTHS 285
                  |.|....|..  :|:||        ..|..|::.  :|..||..|.:.|....|...||
Mouse   228 ------KYGETCFPKG--RFERK--------RNPSRKKQH--ICDECGKHFSQGSALILHQRIHS 274

  Fly   286 EYKPHQCEICNKSFRQMGELRAHIRRHTGDRPYKCMYCDRHFYDRSERVRHERVHTNTRPYACQE 350
            ..||:.|..|.|:|.:...|..|.|.|||::||||:.|.:.|...|..:.|:|:||..:||.|.:
Mouse   275 GEKPYGCVECGKAFSRSSILVQHQRVHTGEKPYKCLECGKAFSQNSGLINHQRIHTGEKPYECVQ 339

  Fly   351 CGKTFTHTAILKNHILSHSAQKNYN 375
            |||:::.::.|..|...|:|:|..|
Mouse   340 CGKSYSQSSNLFRHQRRHNAEKLLN 364

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14710NP_650092.4 zf-AD 9..83 CDD:285071 20/88 (23%)
COG5048 <261..395 CDD:227381 43/115 (37%)
C2H2 Zn finger 264..284 CDD:275368 6/19 (32%)
zf-C2H2 290..312 CDD:278523 7/21 (33%)
C2H2 Zn finger 292..312 CDD:275368 7/19 (37%)
zf-H2C2_2 304..327 CDD:290200 11/22 (50%)
C2H2 Zn finger 320..340 CDD:275368 6/19 (32%)
zf-H2C2_2 335..357 CDD:290200 10/21 (48%)
C2H2 Zn finger 348..368 CDD:275368 6/19 (32%)
C2H2 Zn finger 376..395 CDD:275368 99/415 (24%)
Zfp24NP_001344376.1 SCAN 48..159 CDD:128708 25/136 (18%)
COG5048 <249..329 CDD:227381 29/81 (36%)
Necessary and sufficient for nuclear localization. /evidence=ECO:0000250 251..301 17/51 (33%)
C2H2 Zn finger 253..273 CDD:275368 6/19 (32%)
C2H2 Zn finger 281..301 CDD:275368 7/19 (37%)
COG5048 305..>358 CDD:227381 19/52 (37%)
C2H2 Zn finger 309..329 CDD:275368 6/19 (32%)
C2H2 Zn finger 337..357 CDD:275368 6/19 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.