DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14710 and Sry-beta

DIOPT Version :9

Sequence 1:	NP_650092.4	Gene:	CG14710 / 41393	FlyBaseID:	FBgn0037920	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	69/287 - (24%)
Similarity:	125/287 - (43%)	Gaps:	43/287 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 QEVLDFNGFIINESIEEDEEPNTESPEQILISHMDSYVDDQQMEELIDDKGELVEELSNANTFYE 201
            :::|.:...|||:.:|  ..||:.:....| .::.:|  |:.:..|...:.::.:.|....   :
  Fly    36 KDILKYFEKIINQRLE--LLPNSAACRDCL-EYLFNY--DRLVRNLSQVQRQIADALLGCR---Q 92

  Fly   202 VEYGDEELLMSSAPSPH---PSFKM--------DKQKPG---------RPRKPDAELKFKRKDIN 246
            || |..|....:|....   |:||:        .:::||         :....|.|.:|...|
  Fly    93 VE-GKAETKQQAAKRARVQVPAFKIVQATALKEPERQPGEEDECEEFMKEEMLDEEFQFSEPD-- 154

  Fly   247 AKERGNQPKCKEE-----EKFMCILCGNVFYKKSVFTAHMMTHSEYKPHQ--CEICNKSFRQMGE 304
                .:.|..:||     .:..|.:||.:|..:.|...|:...:..|..|  |.:|....:....
  Fly   155 ----DSMPSSEEEFFTETTEIPCHICGEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEV 215

  Fly   305 LRAHIRRHTGDRPYKCMYCDRHFYDRSERVRHERVHTNTRPYACQECGKTFTHTAILKNHILSHS 369
            |..|:..|.|....:|.|||:.|..:...:||..||.:.:.|.|.:||:.|:.:.::.||::.|.
  Fly   216 LDLHMNLHEGKTELECRYCDKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHD 280

  Fly   370 AQKN-YNCGICCKSFTLLHQLKAHLQT 395
            |::| ..|.:|.:.|......|.||:|
  Fly   281 AEENALICEVCHQQFKTKRTYKHHLRT 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14710	NP_650092.4	zf-AD	9..83	CDD:285071
		COG5048	<261..395	CDD:227381	39/136 (29%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-C2H2	290..312	CDD:278523	5/23 (22%)
		C2H2 Zn finger	292..312	CDD:275368	4/19 (21%)
		zf-H2C2_2	304..327	CDD:290200	8/22 (36%)
		C2H2 Zn finger	320..340	CDD:275368	7/19 (37%)
		zf-H2C2_2	335..357	CDD:290200	9/21 (43%)
		C2H2 Zn finger	348..368	CDD:275368	6/19 (32%)
		C2H2 Zn finger	376..395	CDD:275368	6/18 (33%)
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	4/19 (21%)
		C2H2 Zn finger	231..251	CDD:275368	7/19 (37%)
		C2H2 Zn finger	259..308	CDD:275368	16/49 (33%)
		C2H2 Zn finger	288..303	CDD:275370	3/14 (21%)
		zf-C2H2	315..337	CDD:278523
		C2H2 Zn finger	317..337	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446675
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930