DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14710 and CG6813

DIOPT Version :9

Sequence 1:	NP_650092.4	Gene:	CG14710 / 41393	FlyBaseID:	FBgn0037920	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster

Alignment Length:	400	Identity:	96/400 - (24%)
Similarity:	144/400 - (36%)	Gaps:	118/400 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ILQCRICLGDFEESQMICLFGDKGESDLRKKLELCCRIRVRQSPQLPEKACNSCCEFVQMWFNFR 71
            ||.||||   ......|.||| .|...|.:::.....:.:....::..:.|.:|.:.:|....||
  Fly     3 ILNCRIC---SRSDAPIDLFG-PGNGHLVRQIHSITGVELSCKKEISGQMCTTCLDNLQAAIKFR 63

  Fly    72 QMCLNSQVYWETSSSERPEALAQASDAEYMLYLYENLHLKLGTENQEKEEITAIEEGDEQQEDQS 136
            |.|:.:                                        ||:.:
  Fly    64 QRCIIA----------------------------------------EKQNL-------------- 74

  Fly   137 QEVLDFNGFIINESIEEDEEPNTESPEQILISHMDSYVDDQQMEELIDDKGELVEELSNANTFYE 201
                        |.||.|.:..:..|    |.:.|  :||.|:|..:|: ..|..|:
  Fly    75 ------------ERIECDSKDCSTDP----IIYED--IDDNQIESELDE-SILCPEV-------- 112

  Fly   202 VEYGDEELLMSSAPSPHPSFKMDKQKPGRPRKPDAELKFKRKDINAKERGNQPKCKEEEKFMCIL 266
                 ::|.|.||........::.|                |.|..   |..|       ::|..
  Fly   113 -----KDLPMPSAEKVSAPTSLNHQ----------------KSIGG---GTGP-------YVCPD 146

  Fly   267 CGNVFYKKSVFTAHMMTHSEYKPHQCEI--CNKSFRQMGELRAHIRRHTGDRPYKCMYCDRHFYD 329
            ||.:...||.|..|.:.|:..|...|..  |.:||....||.:|.|.|||::||.|:||.|.|..
  Fly   147 CGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRIHTGEQPYVCVYCPRRFSS 211

  Fly   330 RSERVRHERVHTNTRPYACQECGKTFTHTAILKNHILSHSAQKNYNCGICCKSFTLLHQLKAHLQ 394
            ...|..|.|.|.|.|.|.|..|.|:|..:..|:.|.:.|...:|:.|.:|.|.|..:..|..||.
  Fly   212 SGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLS 276

  Fly   395 TLTHRNKMEQ 404
            :..|:.|.|:
  Fly   277 SNIHKRKEEK 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14710	NP_650092.4	zf-AD	9..83	CDD:285071	17/73 (23%)
		COG5048	<261..395	CDD:227381	49/135 (36%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		zf-C2H2	290..312	CDD:278523	8/23 (35%)
		C2H2 Zn finger	292..312	CDD:275368	8/21 (38%)
		zf-H2C2_2	304..327	CDD:290200	13/22 (59%)
		C2H2 Zn finger	320..340	CDD:275368	8/19 (42%)
		zf-H2C2_2	335..357	CDD:290200	10/21 (48%)
		C2H2 Zn finger	348..368	CDD:275368	6/19 (32%)
		C2H2 Zn finger	376..395	CDD:275368	7/18 (39%)
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	19/139 (14%)
		C2H2 Zn finger	144..164	CDD:275368	7/19 (37%)
		C2H2 Zn finger	172..194	CDD:275368	8/21 (38%)
		zf-H2C2_2	186..211	CDD:290200	14/24 (58%)
		UFD2	<256..>294	CDD:227443	10/30 (33%)
		C2H2 Zn finger	258..280	CDD:275368	7/21 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960