DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14710 and CG6808

DIOPT Version :9

Sequence 1:	NP_650092.4	Gene:	CG14710 / 41393	FlyBaseID:	FBgn0037920	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_001247055.1	Gene:	CG6808 / 41394	FlyBaseID:	FBgn0037921	Length:	375	Species:	Drosophila melanogaster

Alignment Length:	404	Identity:	122/404 - (30%)
Similarity:	180/404 - (44%)	Gaps:	63/404 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 CRICLGDFEESQMICLFGDKGESDLRKKLELCCRIRVRQSPQLPEKACNSCCEFVQMWFNFRQMC 74
            ||.|.....:|.:..||    ||:..|.|.......|:....||::.|..|...::....|...|
  Fly    10 CRTCRKKGTQSTLQSLF----ESNAHKLLISYAGTSVKPDDGLPDQICTVCLMQLEEVDRFLSAC 70

  Fly    75 LNSQVYWETSSSERPEALAQASDAEYMLYLYENLHLKLGTENQE---KEEITA--IEEGD---EQ 131
            ..|..:..   |...:.|:.||       .:|.|..|...|.::   |:.|:.  |||..   :.
  Fly    71 KQSDAHLR---SLVRQTLSSAS-------AFETLEDKDQLEQKKRARKQNISGRLIEENPINFKT 125

  Fly   132 QED-----QSQEVLDFNGFIINESIEEDEEPNTESPEQILISHMDSY-VDDQQMEELIDDKGELV 190
            ||:     :..|:|..|.|  :.....|...|.|:.:.|   |.:.| :.|..::..|.|:.
  Fly   126 QENALETTKDDEILPINKF--SSDFVFDLNVNAENEKDI---HQEDYTISDMDLDREISDQN--- 182

  Fly   191 EELSNANTFYEVEYGDEELLMSSAPSPHPSFKMDKQKPGRPRKPDAELKFKRKDINAKERGNQPK 255
                     |...|..|    |||.:   ....:..:.....:|.|:...   |:..       .
  Fly   183 ---------YSETYSQE----SSAAT---DSIQETSEDYHNLEPSADYVI---DLGV-------A 221

  Fly   256 CKEEEKFMCILCGNVFYKKSVFTAHMMTHSEYKPHQCEICNKSFRQMGELRAHIRRHTGDRPYKC 320
            | |.:|:.|.:|.|.:...|...||...|.:.|.||||:|.|:||....|:.|:|.|||::||:|
  Fly   222 C-EPDKYRCKICSNTYRCLSQLNAHSQVHRKEKDHQCEVCQKTFRAACNLKTHMRTHTGEKPYQC 285

  Fly   321 MYCDRHFYDRSERVRHERVHTNTRPYACQECGKTFTHTAILKNHILSHSAQKNYNCGICCKSFTL 385
            .||.|.|.|.|...:|||:|||.|||||..|||||:.::....|...||::|::.|.:|.|.|.|
  Fly   286 CYCSRRFADNSTHRKHERLHTNERPYACNICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEFRL 350

  Fly   386 LHQLKAHLQTLTHR 399
            .|||.||.::|.||
  Fly   351 KHQLTAHEKSLAHR 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14710	NP_650092.4	zf-AD	9..83	CDD:285071	18/72 (25%)
		COG5048	<261..395	CDD:227381	62/133 (47%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-C2H2	290..312	CDD:278523	11/21 (52%)
		C2H2 Zn finger	292..312	CDD:275368	9/19 (47%)
		zf-H2C2_2	304..327	CDD:290200	12/22 (55%)
		C2H2 Zn finger	320..340	CDD:275368	10/19 (53%)
		zf-H2C2_2	335..357	CDD:290200	16/21 (76%)
		C2H2 Zn finger	348..368	CDD:275368	7/19 (37%)
		C2H2 Zn finger	376..395	CDD:275368	10/18 (56%)
CG6808	NP_001247055.1	zf-AD	9..79	CDD:214871	18/75 (24%)
		C2H2 Zn finger	229..249	CDD:275368	6/19 (32%)
		zf-C2H2	255..277	CDD:278523	11/21 (52%)
		C2H2 Zn finger	257..277	CDD:275368	9/19 (47%)
		zf-H2C2_2	269..293	CDD:290200	12/23 (52%)
		C2H2 Zn finger	285..305	CDD:275368	10/19 (53%)
		zf-H2C2_2	299..321	CDD:290200	15/21 (71%)
		C2H2 Zn finger	313..333	CDD:275368	7/19 (37%)
		C2H2 Zn finger	341..359	CDD:275368	10/17 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I3338
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960