DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14710 and rn

DIOPT Version :9

Sequence 1:	NP_650092.4	Gene:	CG14710 / 41393	FlyBaseID:	FBgn0037920	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_001262343.1	Gene:	rn / 40879	FlyBaseID:	FBgn0267337	Length:	952	Species:	Drosophila melanogaster

Alignment Length:	159	Identity:	55/159 - (34%)
Similarity:	76/159 - (47%)	Gaps:	6/159 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 KEEEKFMCILCGNVFYKKSVFTAHMMTHSEYKPHQCEICNKSFRQMGELRAHIRRHTGDRPYKCM 321
            :|.:.:.|..|...|...|..:.|...|...||::||||.:.|.|:..|:.|||.||||:||||.
  Fly   512 REAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCR 576

  Fly   322 Y--CDRHFYDRSERVRHERVHTNTRPYACQECGKTFTHTAILKNHILSHSAQKN---YNCGICCK 381
            :  |.:.|...|....|.|.|...:|:.|..|.|.|:....|..||..|...|:   :.|..|.|
  Fly   577 HPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEPSLLEHIPKHKESKHLKTHICQYCGK 641

  Fly   382 SFTLLHQLKAHLQTLTHR-NKMEQTIPSS 409
            |:|....|..|:|....| :|....:|.|
  Fly   642 SYTQETYLTKHMQKHAERTDKRPPIVPGS 670

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14710	NP_650092.4	zf-AD	9..83	CDD:285071
		COG5048	<261..395	CDD:227381	49/138 (36%)
		C2H2 Zn finger	264..284	CDD:275368	5/19 (26%)
		zf-C2H2	290..312	CDD:278523	10/21 (48%)
		C2H2 Zn finger	292..312	CDD:275368	10/19 (53%)
		zf-H2C2_2	304..327	CDD:290200	13/24 (54%)
		C2H2 Zn finger	320..340	CDD:275368	6/21 (29%)
		zf-H2C2_2	335..357	CDD:290200	8/21 (38%)
		C2H2 Zn finger	348..368	CDD:275368	7/19 (37%)
		C2H2 Zn finger	376..395	CDD:275368	7/18 (39%)
rn	NP_001262343.1	C2H2 Zn finger	490..510	CDD:275368
		C2H2 Zn finger	519..539	CDD:275368	5/19 (26%)
		zf-H2C2_2	531..556	CDD:290200	9/24 (38%)
		zf-C2H2	545..567	CDD:278523	10/21 (48%)
		C2H2 Zn finger	547..567	CDD:275368	10/19 (53%)
		zf-C2H2_8	550..630	CDD:292531	30/79 (38%)
		zf-H2C2_2	559..586	CDD:290200	14/26 (54%)
		C2H2 Zn finger	575..597	CDD:275368	6/21 (29%)
		C2H2 Zn finger	605..625	CDD:275368	7/19 (37%)
		C2H2 Zn finger	636..656	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100